1 / 15

Stable and state-dependent impulsivity in Bipolar disorder

Stable and state-dependent impulsivity in Bipolar disorder. Maja Milavec , psychologist, Ph. D. student Lilijana Šprah , Assistant Professor and Research Fellow Sociomedical Institute at SRC SASA, Ljubljana, Slovenia. Bipolar disorder.

zeus-alston
Télécharger la présentation

Stable and state-dependent impulsivity in Bipolar disorder

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Stable and state-dependent impulsivity in Bipolar disorder Maja Milavec, psychologist, Ph. D. student Lilijana Šprah, Assistant Professor and Research Fellow Sociomedical Institute at SRC SASA, Ljubljana, Slovenia

  2. Bipolar disorder Any of several mood disorders, usually characterised by alternating episodes of depression and mania or by episodes of depression alternating with mild, non-psychotic excitement.

  3. Impulsivity is a predisposition toward rapid, unplanned reactions to internal or external stimuli without regard to the negative consequences of these reactions to the impulsive individual or to others. (Moeller, Barratt, Dougherty, Schmitz and Swann, 2001)

  4. Impulsivity • A prominent aspect of Bipolar disorder; • manic episode; • can be present during depression; • complications: suicide, substance abuse, complications of manic episodes; • stable or state-dependent; • emotional modulation of cognitive control (attentional bias to positive and negative information).

  5. Aims 1.) Whether emotional valence of stimulus influences cognitive control in bipolar patients compared to healthy individuals. 2.) Whether there is an interaction between stable and state-dependent aspect of impulsivity in bipolar disorder.

  6. Method Participants • 39 bipolar outpatients • 38 healthy individuals (matched for age, gender and years of education)

  7. Instruments Barratt Impulsiveness Scale 11 (BIS-11) • Questionnaire designed to measure impulsiveness (stable aspect). • Three subscales: • attention (intention and cognitive instability), • motor (motor impulsiveness and lack of perseverance), • non-planning (lack of self-control and intolerance of cognitive complexity). (Patton, Standford and Barratt, 1995)

  8. Affective Go/No-Go Task • Computer administered; • pictures of negative, positive and neutral emotional valence taken from International Affective Picture System (IAPS); • 6 blocks with all combinations (negative/positive etc.).

  9. Example: “If the picture in front of you is PLEASANT, press the RED BUTTON on the keyboard AS FAST AS YOU CAN, other way don’t press anything.” Instructions

  10. Reaction times Bipolar outpatients had longer reaction times to emotional stimuli than healthy individuals. * p<0,05; ** p<0,01

  11. Global score Bipolar outpatiens had less correct answers than healthy individuals.

  12. ** p<0,01 Bipolar outpatiens had higher levels of trait impulsivity than healthy individuals.

  13. Bipolar patients with heightened levels of trait impulsivity underestimated • target stimuli with positive valence (r = -0,425; p < 0,01), • distractors with negative (r = -0,331; p < 0,05) and • distractors with neutral (r = -0,417; p< 0,01) emotional valence.

  14. Conclusions • Poorer control of cognitive inhibition • increased levels of impulsivity and other associated cognitive impairments; • emotional valence of stimulus influences cognitive control in bipolar patients compared to healthy subjects; • interaction between stable and state-dependent aspect of impulsivity in bipolar disorder.

  15. Contact maja.milavec@gmail.com

More Related