Modulation of BCL6 Expression in Breast Cancer Cell Lines T47D and MCF-7 In Vitro

DESCRIPTION

This study investigates the modulation of BCL6 expression in breast cancer cell lines T47D and MCF-7 through transient transfection techniques. In panel (a), BCL6 siRNA was used to transiently reduce BCL6 expression in T47D cells, while in panel (b), BCL6 cDNA was transiently introduced into MCF-7 cells to enhance BCL6 levels. The results demonstrate significant alterations in BCL6 expression, highlighting its potential role in breast cancer biology. Statistical significance was noted with a p-value < 0.01.

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Feb 10, 2026

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Modulation of BCL6 Expression in Breast Cancer Cell Lines T47D and MCF-7 In Vitro

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BCL6 BCL6 Supplement Figure 1 GAPDH GAPDH a * * T47D b * * MCF-7 Figure 1. Modulation of the expression of BCL6 in breast cancer cell lines in vitro. (a) BCL6 siRNA was transiently transfected into T47D cells to decrease the expression of BCL6. (b) BCL6 cDNA was transiently transfected into MCF-7 cells to increase the expression of BCL6. **, P < 0.01.