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Human influenza leads to annual outbreaks, with many individuals possessing some immunity to existing strains. However, the emergence of new strains poses significant risks, as humans typically have little to no immunity against them. This can result in pandemics, potentially affecting over 25% of the global population. Once a pandemic is underway, it is estimated that 20% to 50% of the worldwide population may become infected, highlighting the importance of understanding and preparing for influenza's impact on public health.
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