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SIDS Sudden infant death syndrome. DEFINITION . The sudden death of an infant younger than one year of age Remains unexplained after a thorough case investigation, including: performance of a complete autopsy examination of the death scene review of the clinical history.
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DEFINITION • The sudden death of an infant younger than one year of age • Remains unexplained after a thorough case investigation, including: • performance of a complete autopsy • examination of the death scene • review of the clinical history
PATHOGENESIS • Underlying vulnerability (eg, genetic pattern, brainstem abnormality) • A trigger event (eg, airflow obstruction, maternal smoking or infection) • At a vulnerable developmental stage of the central nervous or immune system
Maternal risk factors • Young maternal age • Maternal smoking during pregnancy, drug abuse, alcohol use • Late or no prenatal care • Pregnancy complications -placenta previa, abruptio placenta, premature rupture of membranes, and elevated maternal alpha-fetoprotein
Infant and environmental risk factors • Preterm birth and/or low birth weight • Prone sleeping position • Sleeping on a soft surface and/or with bedding accessories such as loose blankets and pillows • Bed-sharing (eg, sleeping in parents’ bed) • Overheating • Sibling of SIDS victim
הערות נוספות • A history of apnea, apparent life-threatening event (ALTE), or other abnormalities in breathing patterns are not clinically useful predictors of SIDS risk • Car seats • Sleep positioners • Swaddling • Pacifier use • Breastfeeding