Antibody Sequencing Is Available in Creative Biolabs

1. Antibody Sequencing Is Available in Creative Biolabs Generally speaking, antibodies and specific antigens possess high affinity, which plays a major role in the immune system response. Antibodies are connected with the occurrence of a variety of diseases, prevention, and development closely. Furthermore, the research toward antibodies has now become an important part of the research in life science. Scientists from Creative Biolabs have developed “Database Assisted Shotgun Sequencing" (DASS) technology, which provides users with rodent antibody sequencing services. Apart from that, Creative Biolabs has established a solid platform for antibody sequencing as well. There are various antibody sequencing services; de novo sequencing is one of the kind. Taking de novo sequencing of the CDR3 region as an example, it is usually not available in databases because the CDR3 of the light chain is mainly encoded by germline sequences. In addition, a large number of D-segments are modified by terminal transferases. It is typical that only 1-4 AA of a D-segment remain in the matured antibody while the rest is artificial and has to be sequenced de Novo. In fact, various antibody sequencing services in creative Biolabs have been developed based on the next generation antibody sequencing platform, which helps researchers to promote the practical application of DASS technology to a large degree. During the process, all kinds of species such as allotypes of antibodies can be sequenced with 100% coverage. Under such condition, there are a large number of successful cases from Creative Biolabs which meet the customers’ needs. However, antibody sequencing in Creative Biolabs can also meet many difficulties. Through the great efforts made by scientists from the company, with advanced technology and developed methods, Creative Biolabs has overcome the current drawback of sequencing. Meanwhile such sequencing services contain variable plus leader region as well. However, the most important is that the masses of reduced light and heavy chain had better be determined before the beginning of antibody sequencing.

2. Antibody Sequencing in Creative Biolabs Through extensive research, Creative Biolabs has discovered that all isotypes, allotypes and species of antibodies may be successfully sequenced through the De Novo method with 100% total coverage. The company service specifications include the sequencing of the V and J and C segments by DASS, de novo sequencing of the CDR3 region, isobaric amino acids and some other non-standard antibody sequencing. Contact Company: Creative Biolabs Web: http://www.creative-biolabs.com/next-generation-antibody-sequencing.html Email: contact@creative-biolabs.com Phone: 1-631-871-5806 or 44-207-048-3343