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Chapter 3 Blood

Chapter 3 Blood. Section 1 Blood components and its properties. Functions of blood 1. Place of exchange of substances between interstitial fluid and external environment 2. Transport 3. Buffer function 4. To keep body temperature relatively constant 5. Hemostasis 止血

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Chapter 3 Blood

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  1. Chapter 3 Blood Section 1 Blood components and its properties

  2. Functions of blood 1. Place of exchange of substances between interstitial fluid and external environment 2. Transport 3. Buffer function 4. To keep body temperature relatively constant 5. Hemostasis止血 6. Defense function

  3. 1. Components of blood plasma blood cells: red blood cells (erythrocytes) white blood cells platelets Blood volume: 70-80ml/Kg, 7-8% of body weight

  4. Hematocrit血细胞比容 men is about 40～50%, women is about 37～48%.

  5. 2. Physical and chemical propertiesof blood (1) Specific gravity 比重 blood: 1.050～1.060. RBC number plasma: 1.025～1.030. Content of plasma proteins RBC:1.090 ～1.092. hemoglobin

  6. (2) Viscosity粘性Viscosity of plasma is 1.2-1.3 times that of water, viscosity of whole blood is 2.4 times of plasma.

  7. Factors of affecting viscosityhemotocrit血细胞比容

  8. (3)plasma osmolality — 313 mOsm/Kg H20.

  9. Osmotic pressure is determined by the number of particle, instead of the mass of the solute..

  10. At 37℃, 1 osmolality will cause 19300 mmHg osmotic pressure.Plasmaosmolality is 0.313Osm /Kg. H20 0.313×19300 = 5330 mmHg

  11. Colloid胶体 osmotic pressure: maintain intra-and extra-capillary water equilibrium Crystal晶体 osmotic pressure: maintain intra-and extracellular water equilibrium

  12. Isoosmotic solution等渗hyperosmotic solutionhypoosmotic solutionIsotonic solution等张

  13. 3. RBC fragility. 0.42% NaCl solution--begin hemolysis溶血 0.35%NaCl solution--complete hemolysis 4. Plasma pH 7.35-7.45

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