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Project Summary Revisited

Asthma DPI Novel Design Robert J. Toth Annemarie Alderson, Annie Saha, Stephanie Shaulis Timothy Corcoran, PhD 03/29/2005. Project Summary Revisited. To design and develop a dry-powder, single-dose, disposable inhaler

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Project Summary Revisited

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  1. Asthma DPI Novel DesignRobert J. TothAnnemarie Alderson, Annie Saha, Stephanie ShaulisTimothy Corcoran, PhD03/29/2005

  2. Project Summary Revisited • To design and develop a dry-powder, single-dose, disposable inhaler • To create a prototype that is self contained, ruggedly constructed, weather and water proof, lightweight, small, ergonomically designed, and actively mobile • To be used by asthmatic individuals that desire a temporary alternative to traditional devices during physical activity and/or in extreme environment settings

  3. Personal Focus Prior Art (All group members) Anthropometric Data (Annie) Drug & Dosage Data (Stephanie) Develop and computationally test a prototype in Solidworks Excipient Data (Myself) Materials Data (Annemarie) Mentor Suggestion/Feedback (Dr. Corcoran)

  4. Prototype Development Iterative Design Process • Create Solid Model • Perform CFD (COSMOS) • Physiologic boundary conditions • Obtain pneumatics within device consistent with 5 m particle aerosolization • Modify/refine the model • Re-perform CFD testing • Continue cycle until acceptable solid model completed

  5. Prototype Development Summary • 9 solid models developed • Initial CFD indicated rotational flow • Inefficient at dispersing and pneumatically transporting micron-sized particles • Due to boundary conditions • Outlet velocity profile v. outlet pressure • Proper boundary conditions implemented • Streamlined flow patterns observed • Model-8 rapid prototyped through Quickparts

  6. Model-2

  7. Model-3

  8. Model-6

  9. Model-7

  10. Model-8

  11. Prototype

  12. Model-9

  13. Tasks to be Completed • Modify physical prototype – Steph will explain why • Modify/Finalize Model-9 • Order second Quickparts prototype • Finish the design report component of the final deliverable document • Collaborate with my teammates on developing the final presentation • Give the presentation • Graduate, May 1st

  14. A Quick Stop Along the Road to Graduation

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