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ADENOSINE

O 2. uric acid. Xanthine Oxidase. inosine. Adenosine deaminase. cAMP . Inhibition by pentostatin. ATP . ADP . AMP. myocyte or parenchymal cell membrane. macrophage modulation. LPS. (-). LPS. ?. NO-dependent. Neutrophil. Adenosine deaminase. Inhibition. IL-10. (+).

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ADENOSINE

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  1. O2 uric acid Xanthine Oxidase inosine Adenosine deaminase cAMP Inhibition by pentostatin ATP ADP AMP myocyte or parenchymal cell membrane macrophage modulation LPS (-) LPS ? NO-dependent Neutrophil Adenosine deaminase Inhibition IL-10 (+) (-) O2 ? cNOS NO-independent (+) IL-1ß TNF-alpha inosine adenosine iNOS vasodilation receptor Xanthine Oxidase O O 2 2 free radicals free radicals uric acid adenosine kinase ADENOSINE 5' nucleotidases ADENOSINE

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