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Peritoneal &pleural effusions

Peritoneal &pleural effusions. Maryam Mehdizadeh MD,MIAC. case 1: An 83-year-old man with weakness and abdominal pain since a month ago as well as acitis in clinical examination. What is your diagnosis?. High grade malignant lymphoma.

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Peritoneal &pleural effusions

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  1. Peritoneal &pleural effusions MaryamMehdizadeh MD,MIAC

  2. case 1:An 83-year-old man with weakness and abdominal pain since a month ago as well as acitis in clinical examination

  3. What is your diagnosis?

  4. High grade malignant lymphoma

  5. Serous effusions are a well-recognized complication of lymphoma but rarely the detection of lymphoma cells in a serous effusion has been the first morphologic manifestation of the disease .

  6. Staining methods 1.papanicolaou method 2. Air-dried Romanowsky stained preparation

  7. Papanicolaou stained preparations do not allow the same degree of correlation with the various types of lymphoma and leuk- emia that can be achieved by the use of Romanowsky-stained preparations.

  8. However ,not being able to type lymphoma in serous effusions is rarely a disadvantage of pap method ,because nearly all of the patients has already been diagnosed as having lymphoma .

  9. Key features of lymphoma and leukemia 1. Isolated cell only 2. Cells frequently necrotic 3. Morphologic range : from seemingly mature lymphocyte to large cells with polymorphous nuclei

  10. Gastric biopsy

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