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ACTION Registry-GWTG Results: July 1, 2009 – June 30, 2010

ACTION Registry-GWTG Results: July 1, 2009 – June 30, 2010. Current Site Distribution. Active Sites = 621. WA (9). ME (1). VT (0). ND (1). MT (2). MI. NH (1). MN (6). NY (21). OR (10). MA (7). WI (9). SD (3). RI (2). ID (2). MI (11). WY (0). CT (7). PA (29). IA

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ACTION Registry-GWTG Results: July 1, 2009 – June 30, 2010

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  1. ACTION Registry-GWTG Results:July 1, 2009 – June 30, 2010

  2. Current Site Distribution Active Sites = 621 WA (9) ME (1) VT (0) ND (1) MT (2) MI NH (1) MN (6) NY (21) OR (10) MA (7) WI (9) SD (3) RI (2) ID (2) MI (11) WY (0) CT (7) PA (29) IA (6) NJ (8) NE (6) OH (33) DE (1) NV (7) IL (38) IN (19) WV (1) MD (23) VA (17) UT (2) CO (13) KY (5) MO (21) KS (10) DC (1) CA (40) NC (27) TN (20) SC (15) OK (7) AR (2) AZ (5) NM (3) AL (12) GA (14) MS (12) LA (9) TX (77) FL (36) AK (1) PR(2) HI (4) Last updated: 9/22/2010

  3. Baseline Characteristics - STEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  4. Hospital Presentation Characteristics - STEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  5. In-Hospital Outcomes - STEMI *Unadjusted mortality ** Among non-CABG pts ACTION Registry-GWTG DATA: July 1.2009 – June 30, 2010

  6. Use of Reperfusion Therapy for STEMI STEMI N = 26,772 Reperfusion N = 21,972 (82%) Not Eligible for Reperfusion Therapy Contraindication Listed N= 3,195 (12%) No Reperfusion – No Contraindication Listed N = 1,503 (6%) Primary PCI – 89%* Fibrinolytics – 10%* Both PCI + Lytics – 1%* 93% of eligible patients reperfused ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010 * Among patients receiving reperfusion

  7. STEMI – Door to Balloon and Door to Needle Times:Cumulative 12 Month Data ACTION Registry-GWTG DATA: July 1,2009 – June 30, 2010 DTB = 1st Door to Balloon for Primary PCI DTN = Door to Needle for Lytics

  8. STEMI Primary PCI Results -Non-Transfer Patients with DTB  90 mins 73% of the primary PCI patients are not transferred in

  9. STEMI Primary PCI Results - DTB Benchmarks for Transfer-In Patients 1st Door to Balloon < 90 Minutes 1st Door to Balloon < 120 Minutes 27% of the primary PCI patients are transferred in

  10. STEMI Door-to-Balloon Times –Median Times for Transfer In and Non-Transfer In Patients 250 240 230 220 210 200 190 180 170 147 160 150 143 Time (min) 142 140 116 140 130 113 120 112 110 112 100 91 92 91 90 89 77 77 80 75 75 70 62 62 60 60 60 50 48 48 40 46 46 30 20 10 0 Q3 09 Q4 09 Q1 10 Q2 10 Transfer in DTB Times Non-Transfer in DTB Times

  11. STEMI Acute (< 24 hrs) Medications * Heparin and GP IIb-IIIa administered any time during hospitalization ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010 n

  12. STEMI Revascularization Strategy Trends MedicallyManaged PCI CABG ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  13. STEMI Discharge Medications % Use ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  14. STEMI Discharge Interventions ACTION Registry-GWTG DATA: July 1,2009 – June 30, 2010

  15. Baseline Characteristics - NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  16. Hospital Presentation Characteristics -NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  17. In-Hospital Outcomes - NSTEMI *Unadjusted mortality ** Among non-CABG pts ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  18. NSTEMI Acute (< 24 hrs) Medications * Heparin and GP IIb-IIIa administered any time during hospitalization ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  19. NSTEMI Time from Presentation to Procedure ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  20. NSTEMI Acute Medication Overdosing Trends * Infusion (> 15 units/kg/hr) or bolus (> 70 units/kg) # Initial dose (> 1.05 mg/kg) or total 24 hr dose (> 10 mg over recommended) ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  21. NSTEMI Invasive Cardiac Procedures ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  22. NSTEMI Revascularization Strategy Trends Medically Managed PCI CABG ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  23. NSTEMI Discharge Medications ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  24. NSTEMI Discharge Clopidogrel Use byRevascularization Strategies ACTION Registry-GWTG DATA: July 1, 2009– June 30, 2010

  25. NSTEMI Discharge Interventions ACTION Registry-GWTG DATA: July 1, 2009– June 30, 2010

  26. Baseline Characteristics –STEMI vs. NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  27. Age Distribution –STEMI vs. NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  28. Location of First Evaluation –STEMI vs. NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  29. Hospital Presentation Characteristics - STEMI vs. NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  30. In-Hospital Outcomes - STEMI vs. NSTEMI *Unadjusted mortality ** Among non-CABG pts ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  31. Non-CABG Major Bleeding and Transfusion –STEMI vs. NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  32. Acute Medications - STEMI vs NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  33. Discharge Medications - STEMI vs NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

  34. Discharge Interventions – STEMI vs. NSTEMI ACTION Registry-GWTG DATA: July 1, 2009 – June 30, 2010

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