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Intracellular camp - PowerPoint PPT Presentation

Supplementary Figure 1

Supplementary Figure 1. 3. 2,5. 2. 1,5. 1. 0,5. 0. 6. 5. 4. 3. 2. 1. 0. A. WT with FSK+Gen. WT with FSK. lF508del with FSK+Gen. lF508del with FSK. ns. ns. ns. ns. Bicarbonate secretion ( normalized to the rate in FSK-treated F508del as 1). 10 min post peak response.

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Clo

Intracellular cAMP. 3. 25 mM glucose. Vehicle. 2. 20 nM. 1 m M. 1. 50 m M. 0. Clo. Ris. Ola. Quet. Hal. Arip. Zip. 3. 5.6 mM glucose. Vehicle. 2. 20 nM. 1 m M. 1. 50 m M. 0. Clo. Ris. Ola. Quet. Hal. Arip. Zip.

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Intracellular camp - PowerPoint PPT Presentation

Supplementary Figure 1

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