'Pmx 464' diaporamas de présentation

Quinols - Discovery Program

Quinols - Discovery Program. Initiated 1998 - novel structures via oxidation of interesting phenols Rigorous antitumour profiling of resulting new chemical entities Lead compounds identified from 2 novel chemical series (AW 464, AJM 290). In Vitro Antitumour Activity.

587 views • 33 slides

Novel Antitumour Quinols Charles Matthews

450 views • 31 slides

Thioredoxin-targeted Experimental Anti-tumour Quinols Exert Cytotoxicty Following

Thioredoxin-targeted Experimental Anti-tumour Quinols Exert Cytotoxicty Following Activation of Apoptosis Signal-regulating Kinase 1. Charles S Matthews, Tracey D Bradshaw, Eng-Hui Chew, Thilo Hagen and Malcolm FG Stevens. Mechanism of Action: Inhibition of Thioredoxin.

111 views • 1 slides