'Snps' diaporamas de présentation

SNP Discovery and Analysis Application to Association Studies

SNP Discovery and Analysis Application to Association Studies. Mark J. Rieder, PhD Dana Crawford, PhD SeattleSNPs PGA Morehouse University May 2, 2005. Practical Aspects of SNP Association Studies. SNP Discovery: Where do I find SNPs to use in my association studies?

1.08k views • 88 slides

SNP Resources: Finding SNPs, Databases and Data Extraction

SNP Resources: Finding SNPs, Databases and Data Extraction. Debbie Nickerson debnick@u.washington.edu SeattleSNPs. Complex inheritance/disease. Many Other Genes. Variant Gene. Environment. Disease. Diabetes Heart Disease Schizophrenia Obesity Multiple Sclerosis Celiac Disease

792 views • 63 slides

Algorithmic and Statistical Perspectives on Large-Scale Data Analysis

649 views • 55 slides

Genome-wide association studies (GWAS)

Genome-wide association studies (GWAS). Thomas Hoffmann. Outline. GWAS Overview Design Microarray Sequencing Which to use and other censiderations QC Analysis Population stratification adjustment Imputation Replication & Meta-analysis Limitations, missing heritability, and beyond.

2.58k views • 55 slides

Exploring complex diseases using genome-wide association: challenges and strategies

Exploring complex diseases using genome-wide association: challenges and strategies. Li Jin, Ph.D. Fudan University CAS-MPG Partner Institute for Computational Biology. HGM2006, Helsinki. A G C. G G C. Gly. Ser. Positional Cloning. HGM2006, Helsinki. Linkage Disequilibrium.

614 views • 51 slides

SNPs, Haplotypes, Disease Associations

SNPs, Haplotypes, Disease Associations. Algorithmic Foundations of Computational Biology II Course 1. Prof. Sorin Istrail. SNPs and the Human Genome: The Minimal Informative Subset. Overview. Introduction: SNPs, Haplotypes A Data Compression Problem:

722 views • 44 slides

Getting Started

Getting Started. Download and install Haploview http://www.broad.mit.edu/mpg/haploview/index.php. Lab 1. Downloading dense genotype/resequencing data from HapMap and SeattleSNPs Choosing tagSNPs by using Haploview. Yu-Chun Jean Yen yyen@hsph.harvard.edu Bldg.2 Rm. 200.

436 views • 33 slides

Association mapping: finding genetic variants for common traits & diseases

Association mapping: finding genetic variants for common traits & diseases. Manuel Ferreira. Genetic Epidemiology. Queensland Institute of Medical Research Brisbane. WEHI Postgraduate seminar, 31 May 2010. Why?. Understand disease aetiology.

469 views • 33 slides

Debbie Nickerson

Genomics and Population Studies. Debbie Nickerson. Department of Genome Sciences University of Washington debnick@u.washington.edu. The Next Challenge Understanding the link between - DNA sequence Biology/Disease

469 views • 28 slides

Low-Cost, Low-Density Genotyping and its Potential Applications

465 views • 28 slides

Allelic architecture underlying complex disease loci

COMMON DISEASE / COMMON VARIANT HYPOTHESIS. Allelic architecture underlying complex disease loci. Malattie Mendeliane mutazioni altamente penetranti spesso soggette a selezione negativa (varianti rare)

470 views • 27 slides

Authors: Lan Liu , Yonghui Wu,

E fficient A lgorithms for G enome-wide T agSNP S election across P opulations via the Linkage Disequilibrium C riterion. Authors: Lan Liu , Yonghui Wu,. Stefano Lonardi and Tao Jiang. Outline. Introduction The MCTS Model Our Algorithms Experimental Result. Outline. Introduction

368 views • 23 slides

Informative SNP Selection Based on Multiple Linear Regression

Informative SNP Selection Based on Multiple Linear Regression. Jingwu He Alex Zelikovsky. Outline. SNPs, haplotypes, and genotypes Tagging problem formulation Tagging based on multiple linear regression Experimental results. Human Genome. Length of Human Genome (DNA)

359 views • 18 slides

A single-nucleotide polymorphism tagging set for human drug metabolism and transport

A single-nucleotide polymorphism tagging set for human drug metabolism and transport.

379 views • 18 slides

JAMA Ophthalmology Journal Club Slides: VEGFA and VEGFR1 and Response to Anti-VEGF

JAMA Ophthalmology Journal Club Slides: VEGFA and VEGFR1 and Response to Anti-VEGF.

295 views • 11 slides

Selecting SNPs in high-throughput genotyping projects

Selecting SNPs in high-throughput genotyping projects. Joaquín Dopazo Centro de Investigación Príncipe Felipe Valencia http://bioinfo.cipf.es http://www.pupasnp.org http ://pupasview.bioinfo.cipf.es. Design and implementation of a pipeline for high-throughput genotyping at the CeGen.

266 views • 9 slides

Comparing SNPs with CNVs

897 views • 8 slides

Coccidiosis data

282 views • 6 slides

polyomx

www.polyomx.org. Analysis of Single Nucleotide Polymorphisms in Candidate Genes and Application of Machine Learning Techniques for assessing Susceptibility to Breast Cancer in Alberta Women. Dufour J 1 , Wang Y 1,2 , Cass CE 1,3,4 , Greiner R 1,2 , Mackey J 1,3 and Damaraju S 1,3,4

176 views • 1 slides

DM Altshuler et al. Nature 467 , 52-58 (2010) doi:10.1038/nature09298

Haplotype sharing around SNPs and CNPs. DM Altshuler et al. Nature 467 , 52-58 (2010) doi:10.1038/nature09298.

82 views • 1 slides