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Some stuff about cortical network modelling what I done

Some stuff about cortical network modelling what I done. Richard Tomsett 1,2 , Miles Whittington 3 , Mark Cunningham 4 , Marcus Kaiser 2,4

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Some stuff about cortical network modelling what I done

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  1. Some stuff about cortical network modelling what I done Richard Tomsett1,2, Miles Whittington3,Mark Cunningham4, Marcus Kaiser2,4 Institute of Ageing and Health, Newcastle University2. School of Computing Science, Newcastle University3. Hull York Medical School, University of York4. Institute of Neuroscience, Newcastle University OSB Hackathon, UCL, 6th November 2013

  2. Matthew Ainsworth OSB Hackathon, UCL, 6th November 2013

  3. Matthew Ainsworth OSB Hackathon, UCL, 6th November 2013

  4. OSB Hackathon, UCL, 6th November 2013

  5. NB: wrong dimensions in Bush & Sejnowski 1993 OSB Hackathon, UCL, 6th November 2013

  6. Thanks to: • Anna Simon • Mark Cunningham • Marcus Kaiser • BBSRC, Wellcome Trust OSB Hackathon, UCL, 6th November 2013

  7. OSB Hackathon, UCL, 6th November 2013

  8. OSB Hackathon, UCL, 6th November 2013

  9. LFP simulation 100um – 1000um OSB Hackathon, UCL, 6th November 2013

  10. LFP simulation OSB Hackathon, UCL, 6th November 2013

  11. LFP simulation 100um – 1000um OSB Hackathon, UCL, 6th November 2013

  12. LFP simulation Edge Half-way to gamma generating region OSB Hackathon, UCL, 6th November 2013

  13. LFP simulation 100um – 1000um OSB Hackathon, UCL, 6th November 2013

  14. LFP simulation Top Middle Bottom OSB Hackathon, UCL, 6th November 2013

  15. Kawaguchi & Kondo, 2002 OSB Hackathon, UCL, 6th November 2013

  16. “Regular spiking non pyramidal cell” GABAA GABAA Bitufted cell GABAA +GABAB Neurogliaform cell Basket cell GABAA GABAA Axo-axonic cell Pyramidal cell Slide courtesy of Anna Simon

  17. GABAA Other interneurons ? Basket cell Pyramidal cell

  18. 90% basket cell reduction in central 2mm section, replaced by non-basket interneurons (regular spiking) OSB Hackathon, UCL, 6th November 2013

  19. Thanks to: • - Matt Ainsworth (York) • Anna Simon (Newcastle) • Mark Cunningham (Newcastle) • Miles Whittington (York) • Marcus Kaiser (Newcastle) • BBSRC, EPSRC, Wellcome Trust OSB Hackathon, UCL, 6th November 2013

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