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INTRODUCTION TO AUTONOMIC PHARMACOLOGY: Part II Anatomy of peripheral nervous system

INTRODUCTION TO AUTONOMIC PHARMACOLOGY: Part II Anatomy of peripheral nervous system. Peripheral Nervous System. Somatic Nervous System. Autonomic Nervous System. Parasympathetic Nervous System . Sympathetic Nervous System. Selective Activation. Diffuse Activation. Skeletal

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INTRODUCTION TO AUTONOMIC PHARMACOLOGY: Part II Anatomy of peripheral nervous system

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  1. INTRODUCTION TO AUTONOMIC PHARMACOLOGY: Part II Anatomy of peripheral nervous system

  2. Peripheral Nervous System Somatic Nervous System Autonomic Nervous System Parasympathetic Nervous System Sympathetic Nervous System Selective Activation Diffuse Activation Skeletal Muscle Glands, Smooth Muscle & Cardiac Muscle

  3. Peripheral Nervous System Controls Controls smooth & skeletal cardiac muscle muscle & glands Somatic Autonomic Nervous Nervous System System Two One Neuron Neuron Efferent Efferent Limb Limb

  4. Somatic MotorFiber Skeletal Muscle Ach Ganglion Sympathetic Smooth Muscle Cardiac Cells Gland Cells Postganglionic Fiber; Adrenergic Ach NE Ganglion Sympathetic Sweat Glands Ach Ach Preganglionic Fiber; Cholinergic Postganglionic Fiber; Cholinergic Sympathetic EPI/NE Ach Smooth Muscle Cardiac Cells Gland Cells Adrenal Gland Para- sympathetic Ganglion Ach Ach

  5. Radial Muscle of Iris Ciliary Muscle Sympathetic Nervous System (Thoracolumbar Outflow) Sublingual/Submaxillary & Parotid Gland SA & AV Nodes His-Purkinje System Myocardium Pilomotor Muscles Sweat Glands Bronchi/Bronchial Glands Stomach Kidneys Blood Vessels Intestines Paravertebral Ganglia Bladder//Genitalia Prevertebral Ganglia

  6. White Ramus Communicans Gray Ramus Communicans Spinal Nerve Autonomic Nerve Ventral Root Paravertebral Ganglion Prevertebral Ganglion

  7. ADRENAL MEDULLA Chromaffin Cells Epinephrine (+) Dilates Airways (+) Mental Alertness (+) ACTH & TSH (+) Cardiac Output (+) Glycogenolysis (+) Muscle Contraction & Efficiency (+) Fatty Acid Release (-) Intestinal Motility

  8. Parasympathetic Nervous System (Craniosacral Outflow) SA & AV Node Bronchi/Bronchial Glands Sphincter Muscle of Iris Ciliary Muscle Stomach Small Intestines Lacrimal Gland Bile Ducts Gallbladder Submaxillary & Sublingual Glands Kidney Large Intestines Bladder Parotid Gland Genitalia

  9. Most organs receive dual sympathetic and parasympathetic innervation. However, some organs only receive sympathetic innervation: Spleen Sweat Glands Piloerector Muscles Most Blood Vessels

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