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ubiquitin specific peptidase 5 (isopeptidase T)

Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse;

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ubiquitin specific peptidase 5 (isopeptidase T)

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  1. usp5 usp5 Official Full Name Official Full Name ubiquitin specific peptidase 5 (isopeptidase T) Background Background Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse;cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A;late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin;monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end;of the chain (Wilkinson et al., 1995 (PubMed 7578059)). Synonyms Synonyms USP5; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5 (isopeptidase T); ubiquitin carboxyl-terminal hydrolase 5; IsoT; isopeptidase T; ubiquitin isopeptidase T; ubiquitin thioesterase 5; deubiquitinating enzyme 5; ubiquitin Recombinant Recombinant Proteins Proteins  Cell & Tissue Lysates Cell & Tissue Lysates Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price USP5- 681H Recombinant Human USP5 Protein, MYC/DDK-tagged HEK293 Human MYC/DDK +Inquiry USP5- 1182H Recombinant Human USP5, His tagged Baculovirus- Insect Cells Human His +Inquiry USP5- 158H Recombinant Human USP5 protein, His- tagged E. coli Human His +Inquiry

  2. Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price USP5- 3633H Recombinant Human USP5, GST-tagged E. coli Human GST +Inquiry USP5- 17937M Recombinant Mouse USP5 Protein Mammalian Cells Mouse His +Inquiry USP5- 5130R Recombinant Rhesus monkey USP5 Protein, His-tagged Mammalian Cells Rhesus Macaque His +Inquiry USP5- 12776Z Recombinant Zebrafish USP5 Mammalian Cells Zebrafish His +Inquiry Protein Function USP5 has several biochemical functions, for example, cysteine-type endopeptidase activity, omega peptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USP5 itself. We selected most functions USP5 had, and list some proteins which have the same functions with USP5. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function cysteine-type endopeptidase activity Related Protein Related Protein USP15; CTSS; Casp3; USP38; CASP3A; CTS7; CASP6L2; CTSSB.1; CTLA2B; CTSB Function Function omega peptidase activity Related Protein Related Protein JOSD1; USP5; JOSD2; APEH; USP13; GGH; ATXN3L; UCHL5; UCHL1; ATXN3 Function Function protein binding Related Protein Related Protein JAKMIP1; MAP2K3; TEF; ECD; CXADR; BCL2L11; TMEM132D; UTP3; GABARAPL1; NAT2 Function Function ubiquitin binding Related Protein Related Protein OTUB1; UBXN2A; USP16; TRIM32; FAM125A; DYRK2; RNF31; DNAJC2; KCNS1; AUP1 Function Function ubiquitin-specific protease activity

  3. Related Protein Related Protein USP38; ATXN3; UCHL5; VCPIP1; OTUD1; MYSM1; OTUD5; USP19; USP1; USP50 Function Function zinc ion binding Related Protein Related Protein MAN2C1; LASP1; MORC2B; FNTB; ZFAND6; MORC3; BRAP; MTA3; RNF180; RNF2 Interacting Protein USP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP5. DAZAP2; TMEM239; TADA3; UBC; ub6l2_human; RAD23B; USP13; TNFRSF10D; PRKAB1; DVL2; RNF11

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