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Alcoholic Liver Disease

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The liver is the site of alcohol metabolism. Excess of alcohol can overwhelm this capacity and lead to the development of what is called Alcoholic Liver Disease.

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Alcoholic Liver Disease

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  1. Alcoholic LiverDisease • The liver is the site of alcohol metabolism. Excess of alcohol can overwhelm this capacityandleadtothedevelopmentofwhatiscalledAlcoholicLiverDisease. The damagecausedtotheliverbyalcoholcantaketheformoffattyliver,alcoholic hepatitis,orcirrhosis(permanentdamagewithscarring). • According toanestimateof around1.4lakh,peoplediedof cirrhosisrelatedto excessivealcoholconsumptionin theyear2016.Almostalloftheheavydrinkerswill • haveafattyliver. Highertheamountof alcoholconsumptionandlongeritis consumedbearsadirectrelationtothedevelopmentofcirrhosis.Menarelikelyto havecirrhosisthanwomenduetoahigheramountofalcoholconsumed.Women havetwicethehigherriskofdevelopingcirrhosisthanmen. • Stagesof AlcoholicLiverDisease • Thespectrumincludesasimplefattyliver, acutealcoholichepatitis,andalcoholic cirrhosis. Itisthe natural historyof thedisease but theoverlap can occur. • HepaticSteatosis orFattyLiver:Thereisan accumulation of fatin theliver. Thisstage is • reversible with alcoholabstinencei.e.quittingalcoholandmodifyingthe sedentarylifestyle toamoreactiveone.

  2. AcuteAlcoholicHepatitis:Itisthestagein whichalcoholcausesinflammation oftheliver substance.Thereversibilityoftheprocessdependsupon thedamagealreadydone.Long termsurvivalin alcoholichepatitispatientswho stopconsumingalcoholissignificantly greaterthanthepatientswho continuetakingalcohol. • AlcoholicCirrhosis:Thisistheend-stage liver diseasewhichisconsideredtobe • irreversible.Itischaracterized bythescarring oftheliver.Itistheresult ofprolonged and severeliver damage. • Symptoms • The patientswithfattyliverare usuallyasymptomatic. • Alcoholichepatitisvariesin severityandsimilarlythesymptoms.Symptomscanbe • mildsuchasanorexia,weightloss,abdominaldistension,nausea,orvomiting.In severe cases,itcanpresentwithencephalopathy andliverfailure. • Alcoholiccirrhosispresentswithsignsandsymptomsofliverfailuresuchas jaundice,itching,lossofbodyhails,bleedingtendencies,hematemesis,ascites (collectionof fluid intheabdomen),and encephalopathy(sleeplessness,drowsiness, confusionandifsevereunconsciousness). • Diagnosis • Withthesuspicionofthediseasethetreatingdoctorwillbegetting– • Bloodtestssuch ascompletebloodcount,liverfunctiontest, coagulationprofile, andothers. • Ultrasound oftheabdomen or CTscan ofthe abdomenwillalsobedone asthe casemay be. • Aliver biopsymaysometimesbeneeded. • Fibroscanisalso helpfulin assessing theseverityandprogression ofthe disease. • Treatment • Themainstayofthetreatmentofalcoholicliverdiseaseisquittingalcohol.Quitting alcoholmaynotbe easyformany andthereforerequirespropercounselingand rehabilitationprogram.Patientswithseveresymptomsmayrequire hospitalization forworkup and management. Alcoholic hepatitispatientsusually have some nutritional deficiencies.Theyrequirevitaminsupplementationsandagoodprotein and caloricintake.

  3. Livertransplantationis requiredforadvancedcirrhosiswithdecompensation (ascites,encephalopathy,jaundice,varicealbleed).Theearliertheoptionistaken the bettertheprognosis. Conclusion The spectrum of alcoholic liver disease is varied from the reversibility of fatty liver to theirreversibilityofcirrhosis.Alcoholsilentlykillsthedrinkereverypassingday.It destroys thesocial,personal, andprofessionallifeofthe patient. Sources:https://www.narayanahealth.org/blog/alcoholic-liver-disease/amp/ Contactusonline or giveusa callat+91-9667365169/9811392062today! ||

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