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Brody's Human Pharmacology 5th Edition Test Bank By Crespo

Brody's Human Pharmacology 5th Edition Test Bank By Crespo

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Brody's Human Pharmacology 5th Edition Test Bank By Crespo

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  1. Buy Full Version With All Chapters Included At: https://easytestbanks.com/product/brodys-human- pharmacology-5th-edition-test-bank-by-crespo Wecker: Brody’s Human Pharmacology, 5th Edition Chapter 03: Clinical Pharmacokinetics and Issues in Therapeutics Test Bank Multiple Choice 1.Ketamine has a half-life of 2 ½ hours. If used as a continuous infusion at a dosage of 12.5 mg/hr for postoperative pain relief, how long will it take to achieve a practical steady-state concentration? A.5 hours B. 7 ½ hours C.10 hours D.12 ½ hours E.15 hours ANS: D. The practical steady-state concentration is considered to occur after 5 half-lives. 5 times 2 ½ is 12 ½. 2.Which of the following is most likely increased in the average 70-year-old man compared with the average 30-year-old man? A.Body water percentage B.Total lean body mass C.Glomerular filtration rate D.Carotid body baroceptor reflex E.Plasma α-1 acid glycoprotein ANS: E. Of the options given, only α-1 acid glycoprotein plasma levels are increased in the elderly. 3.For a 40-year-old, 75-kg man, drug X has a volume of distribution of 40 L and a clearance of 25 ml/min. Calculate the predicted loading dose of drug X to achieve a plasma concentration of 2 μg/ml. A.20 μg Copyright © 2010 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.

  2. Test Bank 2 B.80 μg C.20 mg D.50 mg E.80 mg ANS: E. The loading dose is obtained by multiplying the goal plasma drug concentration by the volume of distribution. Copyright © 2010 by Mosby, Inc., an Imprint of Elsevier Inc. All rights reserved.

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