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Cisplatin is used as an anti-cancer chemotherapy drug. You can buy highly pureu00a0reference standards of Cisplatin and its impuritiesu00a0fromu00a0Pharmaffiliates Analytics and Synthetics Pvt. Ltdu00a0
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Year 2018 marks 40 since U.S FDA approved the first platinum-based cancer drug, CISPLATIN.Cisplatin is used as an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. Cisplatin (Brand name – Platinol) is injected by the doctors in combination with other drugs to treat several types of cancers.
SideEffects Mode of Action Platinum drugs works by binding primarily to guanine bases in DNA strands which results in forming a platinum bridge. This stops DNA strands from unzipping and replicating, stopping cancer growth and causing cell death. Cancer cells become resistant towards platinum-based drugs, limiting the effectiveness of the drug. Other side-effects include kidney problems, vomiting and bone marrow toxicity.
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