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Hyperplastic Candidosis Ppt Notes

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Hyperplastic Candidosis Ppt Notes

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  1. PowerPoint Presentation Notes: Hyperplastic Candidosis Slide 1: Title Slide - Title: Hyperplastic Candidosis - Subtitle: Oral Potentially Malignant Disorder - Group Members: 1, 2, 3 - Date: Week 13, 30th September 2025 - Slide Layout Suggestion: Large, bold title at top, small group info at bottom; background image of oral cavity or microscope view of Candida. Slide 2: Aim / Objective - Provide an overview of Hyperplastic Candidosis, including: - Definition and epidemiology - Causes - Clinical signs and symptoms - Clinical assessment - Investigations - Management and prevention - Layout: Bullet points; use simple icons for each objective. Slide 3: Definition - Hyperplastic Candidosis (Chronic Hyperplastic Candidiasis) - White oral lesion caused by Candida species, cannot be wiped off - Potentially malignant disorder due to risk of progression to oral squamous cell carcinoma (Neville et al., 2020) - Visual: Diagram of oral lesion showing white adherent patch. Slide 4: Epidemiology - More common in adults, especially middle-aged men (Ramage et al., 2019) - Prevalence relatively rare compared to other oral candidiasis - Associated with immunosuppression, smoking, alcohol use (Patil et al., 2015) - Visual: World map or bar chart of prevalence, patient demographic illustration. Slide 5: Causes / Etiology - Candida albicans infection (primary cause) - Predisposing factors: - Immunocompromised state (HIV, diabetes, chemotherapy) - Smoking, poor oral hygiene, chronic irritation - Use of corticosteroids or broad-spectrum antibiotics (Akpan & Morgan, 2002) - Visual: Flowchart showing causes leading to lesion formation. Slide 6: Clinical Signs and Symptoms - White, adherent patches on oral mucosa, especially buccal mucosa - Cannot be wiped off; may cause mild discomfort or burning - Often asymptomatic; sometimes associated with fissured tongue or leukoplakia (Ramage et al., 2019) - Visual: High-quality photo of hyperplastic candidosis lesion. Slide 7: Clinical Assessment Steps 1. Patient history: medical conditions, medications, lifestyle habits, lesion progression 2. Oral examination: inspect lesion location, size, color, texture 3. Palpation: assess consistency, induration, tenderness 4. Risk assessment: evaluate potential malignant transformation - Visual: Flow diagram of assessment steps. Slide 8: Investigations - Microbiological tests: swab culture to identify Candida species - Histopathology: biopsy to rule out dysplasia or malignancy - Blood tests: check for immunosuppression (HIV, diabetes) (Patil et al., 2015) - Visual: Lab test icons, biopsy image, culture petri dish image. 1

  2. Slide 9: Management - Antifungal therapy: - Topical: Nystatin or Clotrimazole lozenges - Systemic: Fluconazole for refractory cases - Address predisposing factors: improve oral hygiene, stop smoking, control systemic conditions - Regular follow-up for early detection of malignant transformation (Neville et al., 2020) - Visual: Medication icons, checklist for risk factor modification. Slide 10: Prevention - Maintain good oral hygiene - Avoid tobacco and alcohol - Treat systemic predisposing conditions - Regular dental check-ups and monitoring of high-risk patients - Visual: Preventive care icons, infographic style. Slide 11: Summary / Key Points - Hyperplastic Candidosis is a potentially malignant oral lesion caused by Candida infection - Cannot be wiped off, may show dysplastic changes - Early diagnosis and antifungal treatment essential - Risk factor modification and monitoring prevent progression to malignancy - Visual: Highlight key points with bold icons or boxes. Slide 12: References (Harvard Style) - Akpan, A. & Morgan, R., 2002. Oral candidiasis. Postgraduate Medical Journal, 78(922), pp.455-459. - Neville, B.W., Damm, D.D., Allen, C.M. & Chi, A.C., 2020. Oral & Maxillofacial Pathology. 4th ed. St. Louis: Elsevier. - Patil, S., Rao, R., Sanketh, D., Babu, N.K. & Acharya, S., 2015. Chronic hyperplastic candidiasis and its association with malignant transformation: a review. Journal of Oral and Maxillofacial Pathology, 19(1), pp.108-113. - Ramage, G., Saville, S.P., Thomas, D.P. & López-Ribot, J.L., 2019. Candida biofilms: an update. Eukaryotic Cell, 18(1), pp.13-19. Slide 13: Questions / Discussion - Invite audience questions - Encourage discussion on clinical cases and risk factors - Visual: Question mark icon or interactive slide layout 2

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