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Statistical Analysis of Mouse Gut Microbiota

Alex Tran Computer Systems Lab 2009-2010. Statistical Analysis of Mouse Gut Microbiota. Abstract.

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Statistical Analysis of Mouse Gut Microbiota

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  1. Alex Tran Computer Systems Lab 2009-2010 Statistical Analysis of Mouse Gut Microbiota

  2. Abstract • The mouse gut microbiotal community is the population of bacteria, which inhabit the digestive track of a given population of mice. The ability to understand the microbiotal community has implications, which extend beyond mice and into factors of human obesity and the dietary needs of the human body. Computational genomics is an emerging field, which blends both biology and computer science, to analyze genes. This study seeks to utilize several methods emerging within computational genomics to analyze the gut microbiome of mice to observe the effects of varying diets on the gut microbiotal community, as well as create a universal and user friendly tool for researchers to utilize when studying any gut microbiome.

  3. Introduction • Genomics • Gut Microbiota • Mouse Digestive Tract http://esd.lbl.gov/img/HOME/a_gut_feeling.jpg

  4. Background • OB/OB mice • Human Microbiome Project http://www.use.com/media/2008/0208/35680/p_001.jpg

  5. Development • Python • Tkinter • I/O intensive http://tamago-club.cocolog-nifty.com/photos/uncategorized/piyo070219b-thumb.png

  6. Objectives • User Friendliness • Efficiency • Universal Compatibility • Hugenholtz • RDP

  7. Current Status • Shell GUI • Reads standard format files • Two taxonomic trees • Ability to specify taxonomy used

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