1 / 13

Machine Learning group meeting

This meeting presented preliminary findings from the Rice Genome Annotation Project, focusing on predicted introns across different chromosomes and criteria. Key results included the number and types of introns identified, with significant statistical analyses conducted using Chi-squared tests. For intron retention, a Chi-squared value of 584.436 was observed with a p-value of less than 0.0001, highlighting a strong correlation. The results discuss the predicted genes with constitutive and alternative splicing events, emphasizing the methodology and data used in the analysis.

adlai
Télécharger la présentation

Machine Learning group meeting

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Machine Learning group meeting Yiming Zhang 02/03/2012

  2. Preliminary results Number of introns predicted in different chromosomes and under different criteria

  3. Preliminary results Expected and observed percentage of introns in different chromosomes

  4. Preliminary results • For intron retention, Chi squared equals 8.092 with 4 degrees of freedom. The two-tailed P value equals 0.0883. • For constitutive intron, Chi squared equals 4.294 with 4 degrees of freedom. The two-tailed P value equals 0.3677

  5. Preliminary results Number of genes which is predicted to have all introns constitutively or alternatively spliced (at least 2 introns per gene) under different criteria

  6. Dataset and model • Rice Genome Annotation Project (Michigan State Univ.) genome sequence and gff3 annotation version 7.0. • After removing redundancy and the introns or their flanking exons which are shorter than 20 nt, 196,290 introns and 44,037 genes have been used. • OS specific model (trained by RF with 200 trees) has been used to make prediction.

  7. Preliminary results Number of introns predicted under different criteria and number of different kinds of introns per gene

  8. Preliminary results Number of introns predicted in different gene region and under different criteria

  9. Preliminary results Number of introns predicted in different chromosomes and under different criteria

  10. Preliminary results Number of introns predicted in different chromosomes and under different criteria

  11. Preliminary results Expected and observed percentage of introns in different chromosomes

  12. Preliminary results • For intron retention, Chi squared equals 584.436 with 11 degrees of freedom. The two-tailed P value is less than 0.0001. • For Constitutive intron, Chi squared equals 443.521 with 11 degrees of freedom. The two-tailed P value is less than 0.0001

  13. Preliminary results Number of genes which is predicted to have all introns constitutively or alternatively spliced (at least 2 introns per gene) under different criteria

More Related