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1.  Sign in Join   Cart (0)  ENTER SEARCH TERM   Dopa Rush: Best Dopamine Activators Brian Turner Posted on September 18 2018 By: Robert A. Schinetsky    Neurotransmitters, nootropics, and all things neurohacking are a hot topic these days as we seek to enhance and elevate our cognitive function and productivity, all while trying to stave off cognitive decline. This surge in all things “neuro” related has been prompted by our increased understanding of the human brain and a fervert frenzy to ?nd ways to “hack” anything and everything about our lives. × Did you know you can earn points for signing up, making purchases and more?  Amidst this talk of increasing productivity and brain function, you’ve no doubt heard about something called dopamine and that it plays a pivotal role in your ability to get things done. But, what is dopamine, why is having it good, and more importantly, how do you get more dopamine? LEARN MORE  We’ve got all that answered ahead, along with the best dopamine activating supplements you can ?nd.  Reward Points

2. What is Dopamine and What Does It Do?  Dopamine is one of your body’s primary “happy” neurotransmitters that’s heavily involved in motivation and reward. It gives your body the “kickstart” it needs to pursue an objective and then imbues you with a surge of satisfaction when you’ve met your objective.  But that’s not all dopamine does. It’s also serves many other important roles in the body impacting memory, learning, attention, creativity, movement, mood, and even sleep.[1,2] Plus, recent research has even indicated that dopamine can play a pivotal role in how we make decisions, which can impact our chance to be successful in work and life.[3]  Basically, dopamine can help you be more awesome at just about anything you want to do, physically or mentally. Without dopamine, you’d frankly be quite un-human, as it affects how we perceive and interact with each other and our environment.  So, how do you increase dopamine? Ways to Increase Dopamine  There’s no shortage of ways to increase dopamine, both through lifestyle changes as well as dietary supplements. Let’s ?rst discuss the little things you can do each day to boost dopamine production in the body, and then we’ll get to the best dopamine activating supplements.  First up, and one of the easiest ways to increase dopamine is by eating a diet high in protein. Dopamine is synthesized in the body from Tyrosine, one of the nine essential amino acids your body needs to build proteins. By consuming complete protein sources (beef, chicken, pork, etc.), you’re providing your body with the “building blocks” in needs to generate dopamine. × Did you know you can earn points for signing up, making purchases and more?  Second is exercise. Research has shown that exercise increases dopamine.[4,5] Steady-state, high intensity interval training, or heavy resistance training -- it all helps boost dopamine. So in addition to getting ?t and burning fat, you’re also improving your cognitive function and mood! LEARN MORE  A third way to increase dopamine is by listening to or performing music. Various studies have noted that the brain releases dopamine when listening to pleasurable music.[6,7]  Reward Points

3.  A fourth and ?nal way to naturally boost dopamine levels is through restorative practices, such as yoga or meditation.[8,9] Even getting a massage has been noted to increase dopamine release in the body!  Now, let’s take a look at some of the best supplements for increasing dopamine. Best Dopamine Activators Caffeine  Of all the substances (legal substances, that is) capable of boosting dopamine levels, none are more powerful than caffeine.  Widely reputed for its ability to ignite energy levels, motivation, and mood, caffeine is the consummate dopamine activator. It’s available damn near everywhere you look these days from pre workout to energy drinks to peanut butter and even protein powder! In fact, caffeine’s performance-enhancing effects are in large part due to its ability to stimulate release of dopamine.  Caffeine increases alertness and energy by blocking (antagonizing) adenosine receptors while also causing an increase in dopamine, noradrenaline, and glutamate.[10] Additional research has noted that caffeine also may upregulate availability and af?nity of dopamine receptor D2 and D3.[11] And still other research notes that caffeine supports higher dopamine concentration in regions of the brain associated with attention.[12]  As powerful as caffeine is when it comes to prompting dopamine release in the body, it’s also important that your brain has the “raw materials” it needs to synthesize dopamine, and that’s where our next great dopamine boosting supplement comes in... × Did you know you can earn points for signing up, making purchases and more? Tyrosine  We mentioned the importance of tyrosine in the production of dopamine above when discussing diet, but that’s not the only way you can get tyrosine. You can also supplement with free form tyrosine. LEARN MORE Studies have noted that tyrosine supplementation increases dopamine levels in the brain.[13] Moreover, additional research has documented that tyrosine supplementation signi?cantly enhances cognitive performance, particularly during acute  Reward Points

4. stressful or cognitively demanding scenarios when dopamine can be temporarily depleted.[13,14] Velvet Bean (a.k.a. Mucuna Pruriens)  Velvet bean is a tropical legume native to Asia and Africa that is loaded with a compound known as L-Dopa.  In case you weren’t aware, L-Dopa is the direct precursor to dopamine production in the brain[15], and studies have noted that supplementing with L-Dopa helps boost dwindling dopamine levels.[15,16] In fact, L-Dopa is such a potent dopamine activating ingredient, researchers have even begun to explore its use as a possible treatment for Parkinson's disease, which is caused by declining dopamine levels.  Theacrine  Up next is another powerful dopaminergic compound as well as a close cousin of caffeine.  The ingredient we’re referring to is none other than theacrine.  Chemically similar to caffeine, theacrine is a methyluric acid derived from kucha that stimulates release of dopamine similar to caffeine[17], but does so in a much “smoother” manner than that of caffeine.  Additionally, research has noted that theacrine does NOT come with the tolerance build up of caffeine, which is a very good thing, if you’re wanting to use the compound frequently to increase dopamine levels.  On its own, theacrine is a pretty solid option for boosting dopamine, but it really shines when combined with caffeine, as research indicates there’s some synergism between the two compounds.[18] Combining the two can lead to greater concentration, awareness and motivation which bodes well for better productivity and performance. × Did you know you can earn points for signing up, making purchases and more? Folic Acid  Finally, we have folic acid, which may be the most underrated dopamine activating supplement around. Folic acid is a highly bioavailable form of vitamin B9, which is often used to combat feelings of sluggishness or depression. LEARN MORE  Reward Points

5.  Where folic acid enters the dopamine production equation is that it is required for the production of an important cofactor needed for the synthesis of dopamine, BH4.[19]  Research has noted that low folic acid levels are associated with reduced dopamine levels, which themselves are linked to depression. As such, it makes sense that by increasing folic acid, we’re providing more of the “supporting cast” that’s needed to create dopamine.  This is similar in a way to consuming more tyrosine, in that you’re giving your body all of the essential raw materials it needs for optimal dopamine production. WIth greater amounts of the primary substrate (i.e. tyrosine) along with ample supply of the rate-limiting enzyme that regulates dopamine production (i.e. BH4), you have everything you need for free-?owing dopamine.  Now, it can be rather time consuming, laborious, and expensive to source each of these ingredients, then combine them all at the right doses to maximize dopamine production.  Fortunately, we’ve done all the hard work for those of you looking to boost productivity and performance with Dopa Rush! Dopa Rush -- Dynamite Dopamine Activator  Dopa Rush is the premier dopamine activating supplement on the market that helps you get more done no matter how tired, frustrated, or “foggy” you may be. Using a synergistic combination of powerful dopamine activating supplements including caffeine, theacrine, tyrosine, velvet bean, and folic acid, Dopa Rush takes a holistic approach to maximizing dopamine production in the body. × Did you know you can earn points for signing up, making purchases and more?  Grab your bottle today and see how boosting your dopamine levels can ignite your creativity, fuel your passion, and help you get the job done rain or shine. LEARN MORE  Reward Points

6.   References 1. Puig, M. V., Rose, J., Schmidt, R., & Freund, N. (2014). Dopamine modulation of learning and memory in the prefrontal cortex: insights from studies in primates, rodents, and birds . Frontiers in Neural Circuits . Retrieved from https://www.frontiersin.org/article/10.3389/fncir.2014.00093 2. Arias-Carrion, O., & Poppel, E. (2007). Dopamine, learning, and reward-seeking behavior. Acta Neurobiologiae Experimentalis, 67(4), 481–488. 3. Treadway MT, Buckholtz JW, Cowan RL, et al. Dopaminergic Mechanisms of Individual Differences in Human Effort-Based Decision-Making. J Neurosci. 2012;32(18):6170 LP-6176. 4. Chen, C., Nakagawa, S., Kitaichi, Y., An, Y., Omiya, Y., Song, N. Kusumi, I. (2016). The role of medial prefrontal corticosterone and dopamine in the antidepressant- like effect of exercise. Psychoneuroendocrinology, 69, 1–9. https://doi.org/10.1016/j.psyneuen.2016.03.008 5. Sutoo, D., & Akiyama, K. (2003). Regulation of brain function by exercise. Neurobiology of Disease, 13(1), 1–14. 6. Zatorre, R. J. (2015). Musical pleasure and reward: mechanisms and dysfunction. Annals of the New York Academy of Sciences, 1337, 202–211. https://doi.org/10.1111/nyas.12677 7. Mavridis, I. N. (2015). Music and the nucleus accumbens. Surgical and Radiologic Anatomy : SRA, 37(2), 121–125. https://doi.org/10.1007/s00276- 014-1360-0 8. Pal R, Singh SN, Chatterjee A, Saha M. Age-related changes in cardiovascular system, autonomic functions, and levels of BDNF of healthy active males: role of yogic practice. Age. 2014;36(4):9683. doi:10.1007/s11357-014-9683-7. 9. Young SN. Biologic effects of mindfulness meditation: growing insights into neurobiologic aspects of the prevention of depression. Journal of Psychiatry & Neuroscience : JPN. 2011;36(2):75-77. doi:10.1503/jpn.110010. 10. Cappelletti S, Daria P, Sani G, Aromatario M. Caffeine: Cognitive and Physical Performance Enhancer or Psychoactive Drug? Current Neuropharmacology. 2015;13(1):71-88. doi:10.2174/1570159X13666141210215655. 11. Volkow ND, Wang G-J, Logan J, et al. Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain. Translational Psychiatry. 2015;5(4):e549-. doi:10.1038/tp.2015.46. × Did you know you can earn points for signing up, making purchases and more? LEARN MORE  Reward Points

7. 12. Meeusen, R., Roelands, B., & Spriet, L. L. (2013). Caffeine, exercise and the brain. Nestle Nutrition Institute Workshop Series, 76, 1–12. https://doi.org/10.1159/000350223 13. Steenbergen, L., Sellaro, R., Hommel, B., & Colzato, L. S. (2015). Tyrosine promotes cognitive ?exibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia, 69, 50–55. https://doi.org/10.1016/j.neuropsychologia.2015.01.022 14. Jongkees, B. J., Hommel, B., Kuhn, S., & Colzato, L. S. (2015). Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review. Journal of Psychiatric Research, 70, 50–57. https://doi.org/10.1016/j.jpsychires.2015.08.014 15. Lampariello LR, Cortelazzo A, Guerranti R, Sticozzi C, Valacchi G. The Magic Velvet Bean of Mucuna pruriens. Journal of Traditional and Complementary Medicine. 2012;2(4):331-339. 16. Hornykiewicz O. L-DOPA. Journal of Parkinson’s Disease. 2017;7(Suppl 1):S3- S10. doi:10.3233/JPD-179004. 17. Taylor L, Mumford P, Roberts M, et al. Safety of TeaCrine®, a non- habituationg, naturally-occuring purine alkaloid over eight weeks of continuous use. J Int Soc Sports Nutr. 2-16;13(1):1-14. doi:10.1186/s12970-016-0113-3. 18. Access O. Proceedings of the Fourteenth International Society of Sports Nutrition (ISSN) Conference and Expo. J Int Soc Sports Nutr. 2017;14(s2):31. doi:10.1186/s12970-017-0188-5 19. Homma, D., Katoh, S., Tokuoka, H., & Ichinose, H. (2013). The role of tetrahydrobiopterin and catecholamines in the developmental regulation of tyrosine hydroxylase level in the brain. Journal of Neurochemistry, 126(1), 70–81. https://doi.org/10.1111/jnc.12287  Recent Posts ARE ALL COVID-19 VACCINES CREATED EQUAL? Feb 09 2021 By Steve Blechman   Coronavirus cases are falling in many parts of the country. More than 40 million Americans have b... New Research: Blood Flow Restriction (BFR) Training and Betaine for Enhanced Muscle Growth Feb 02 2021 By Michael J. Rudolph Ph.D. Senior Science Editor               Synergy is a phenomenon that occurs when combining on... × Did you know you can earn points for signing up, making purchases and more? COLD SWEAT: WINTER WORKOUTS BURN MORE FAT! Jan 27 2021 By Steve Blechman   The coronavirus and pandemic have forced many gyms to close. It has caused some hardcore ?tness ... LEUCINE: THE #1 ANABOLIC TRIGGER! Prevent Muscle Loss With Aging Jan 20 2021 By Steve Blechman   A new study published in the December 16th issue of The American Journal of Clinical Nutrition sa... LEARN MORE NEW 50,000 PEOPLE STUDY SUPPORTS HEALTH BENEFITS OF BROWN FAT! Jan 13 2021  Reward Points

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