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Insulin IGF-1 Insulin IGF-1

Laron syndrome with GHR* mutation. A. Western diet High glycemic load Milk: whey proteins. B. Leu Trp. Serotonin. GH Glucose GIP GH. PRL. GHR* GHR* GHR GHR. IGF-1. IGF-1.

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Insulin IGF-1 Insulin IGF-1

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  1. Laron syndrome with GHR*mutation A Western diet High glycemic load Milk: whey proteins B Leu Trp Serotonin GH GlucoseGIPGH PRL GHR* GHR* GHR GHR IGF-1 IGF-1 InsulinIGF-1 Insulin IGF-1 Nuclear FoxOs Nuclear FoxOs Reduced linear growth, dwarfismIncreased linear growth, tall people low oxidative stress, anti-aging signalinghigh oxidative stress, pro-aging signaling low prevalence of acne, diabetes, cancer high prevalence of acne, diabetes, cancer

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