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INSULIN

INSULIN. By Monica Landoni. Why is this protein useful?. Regulator of blood glucose levels Hormone responsible of fattening Important role in protein synthesis (new proteins are formed) Stimulates mitosis.

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INSULIN

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  1. INSULIN By Monica Landoni

  2. Why is this protein useful? • Regulator of blood glucose levels • Hormone responsible of fattening • Important role in protein synthesis (new proteins are formed) • Stimulates mitosis

  3. Insulin (AKA Peptide Hormone) was discovered in 1922 by Frederick Grant Banting and John James Richard Macleod Its first structure level consists of 51 amino acids that form two polypeptide chains

  4. Secondary structure (simple 3D form) Some of the joined amino acid coil to form short sections of alpha helix, which stabilizes the structure. Other amino acids give a turn to the amino acid chains so the overall structure is fairly compact. A Chain  Blue B Chain  Red

  5. The structure is further stabilized by the appearance of disulphide bridges Insulin can form into granules consisting of hexamers due to interactions between hydrophobic surfaces. Tertiary Structure and Quaternary Structure

  6. Diabetes If there’s a loss of insulin in the body, it will start to use fat as an energy source which can then affect other parts and functions of the body and encourage diabetes.

  7. Type I  Body completely without insulin. Patients are required to do regular insulin injections to control metabolism. Type II  Sufferers are insulin resistant and/or have low production levels. Will require some form of meditation to control blood glucose levels in the body. Eventually they may require regular injection of insulin.

  8. Bibliography • "Levels of Proteinstructure, Exemplified by Insulin." Insulin. N.p., n.d. Web. 02 Feb. 2013. • "So What Does Insulin Do?" Diabetes Forum and Blog Join To Discuss Diabetes Symptoms Treatments Diets and More RSS. N.p., n.d. Web. 02 Feb. 2013. • "Insulin." Wikipedia. Wikimedia Foundation, n.d. Web. 02 Feb. 2013.

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