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ObTiMA – Ontology based tral management system for ACGT

ObTiMA – Ontology based tral management system for ACGT. Fatima Schera, IBMT Workshop on European-Japanese Research Collaboration in Medical ICT, Sapporo, 14.-15. September 2009. setup automatically. Main Components. Patient Data Management System. TrialBuilder. Administration.

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ObTiMA – Ontology based tral management system for ACGT

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  1. ObTiMA – Ontology based tral management system for ACGT Fatima Schera, IBMT Workshop on European-Japanese Research Collaboration in Medical ICT, Sapporo, 14.-15. September 2009

  2. setup automatically Main Components Patient Data Management System TrialBuilder Administration Master Protocol Personal Data Clinical Data Treatment Plan User, Roles and Rights,.. Trial Outline Builder Trial Database CRFBuilder Ontology Viewer Wrapper Services (SPARQL ) Mapping file CRF Repository ACGT Master Ontology ACGT-Mediator

  3. Patient data management Physician Patient Therapy plan Personal data Trial chairman Administration Trial Trial outline Consultant Researcher (person, tool) Patient Metadata Hospital CRF CRF CRF Constraints User Clinical data (CRF) Clinical data (CRF) Clinical data (CRF) ObTiMA: real live process ACGT ObTiMA System Trial and CRF Repository User roles and rights Manage- ment Web application Trial registration • ACGT Trial Builder: • Trial outline builder • CRF creator ACGT Master Ontology MadDRA, LIONC, … SAE/SUSAR registration Report Data export module Statistical centre Communication/ consultation ACGT mediator OGSA DAI Service

  4. Technical realisation Presentation Layer JavaServer Faces (IceFaces) Controller Layer Spring security Business/Service Layer Spring Security (aspects) Domain objects (POJOs) Hibernate Persistence/Data Mapper Layer (O/R Mapper) Data access Layer DAO interfaces DAO implementations

  5. Demonstrator steps • Show how a trial can be set up with the Trial Builder • Show how patients can be managed with the patient data management system • Show the administration module incl. the secure access to several parts of the system depending on the role of the user • Show the data export module • Show how the trial data can be queried with the ontology based mediator

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