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HAZARDOUS SUBSTANCES

HAZARDOUS SUBSTANCES

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HAZARDOUS SUBSTANCES

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  1. HAZARDOUS SUBSTANCES HSNO Class 6 Toxics

  2. Class 6 - Toxicity • 6.1 Acutely toxic • 6.3 Skin irritant • 6.4 Eye irritant • 6.5 Sensitisation • 6.6 Mutagen • 6.7 Carcinogen • 6.8 Reproductive • 6.9 Target organ/system

  3. Toxicity • Acute toxicity thresholds • LD50 </= 5000 mg/kg body weight by oral or dermal exposure • Any mortality or clinical signs of significant adverse biological effect as a result of acute exposure by oral and inhalation routes • other reliable data indicates potential for, or evidence of significant acute toxic effects in humans

  4. Toxicity • Skin and eye irritation • Sensitisation - positive evidence on challenge of respiratory sensitisation or skin contact • Specific respiratory hypersensitivity in humans includes asthma, rhinitis, and alveolitis

  5. Toxicity • Mutagencity • Carcinogenic effects • Reproductive/developmental effects • Target organ/systemic effects • Toxicity mixture rules

  6. Handling Controls • Know the substance and risks • Route of exposure - inhalation, skin, ingestion • Personal Protective Equipment • Spill, storage, disposal • Health monitoring • Environmental Monitoring

  7. Tracking and Storage • Classes 6.1A, B, & C are tracked substances • Give consideration of locking up these categories