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Comprehensive Review of Antiparkinson Drugs and Their Mechanisms of Action

Explore the effectiveness and mechanisms of action of key antiparkinson drugs like Benztropine, Bromocriptine, Carbidopa, Deprenyl, Entacapone, Levodopa, Pramipexole, Ropinirole, and Trihexyphenidyl. Understand how these medications target different pathways to manage Parkinson's symptoms.

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Comprehensive Review of Antiparkinson Drugs and Their Mechanisms of Action

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  1. 2003-2004Review ofAntiparkinson drugs 20 December 20192:05 PM

  2. Benztropine • AnticholinergicAntiparkinson • Muscarinic receptor antagonist

  3. Bromocriptine • Antiparkinson • Dopamine (D2) agonistInhibits prolactin release

  4. Carbidopa • Antiparkinson • Peripheral dopa decarboxylase inhibitor

  5. Deprenyl/selegiline • Antiparkinson • Monoamine oxidase B inhibitor(MAO-I)Potentiates effects of L-Dopa

  6. Entacapone • Antiparkinson • Peripheral catechol-o-methyltransferase inhibitor

  7. Levodopa • Antiparkinson • Dopamine precursor

  8. Pramipexole • Antiparkinson • Dopamine agonist (non-ergot)

  9. Ropinirole • Antiparkinson • Dopamine agonist (non-ergot)

  10. Trihexyphenidyl • Antiparkinson • Antimuscarinic

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