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Investigation of P-IkBa and a-Tubulin Response to Staurosporine and Other Compounds in µM

This dataset explores the effects of various concentrations of staurosporine and other compounds (such as U-73122, genistein, and LY294002) on the phosphorylation of IkBa and levels of a-tubulin. Measurements were taken across multiple concentrations and conditions, indicating a detailed analysis of their influence on cell signaling pathways, particularly in relation to P-IkBa. The findings contribute to our understanding of cellular response mechanisms and could have implications for therapeutic applications.

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Investigation of P-IkBa and a-Tubulin Response to Staurosporine and Other Compounds in µM

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  1. A B H-7 (µM) staurosporine (µM) - - 5 10 15 30 - - 0.03 0.1 0.2 0.4 P-IkBa a-tubulin - A4 A4 A4 A4 A4 - A4 A4 A4 A4 A4 C D E F 48/80 (µM) U-73122 (µM) AG 18 (µM) genistein (µM) - - 1 6 - - 12.5 25 - - 120 160 - - 10 60 P-IkBa a-tubulin - A4 A4 A4 - A4 A4 A4 - A4 A4 A4 - A4 A4 A4 G H I J GDPb (mM) GF 109203X (µM) suramin (mM) LY294002 (µM) - - 2 12 - - 0.2 0.4 - - 0.1 0.3 - - 50 P-IkBa a-tubulin - A4 A4 A4 - A4 A4 A4 - A4 A4 A4 - A4 A4

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