SlideServe
Télécharger Obtenir Pro
Menu
Accueil Pro
Préférences
ApparenceLight Aide et commentaires
© SlideServe · v2026

Differential Diagnosis of Polycythemia Vera

anneke avatar
anneke
14 diapositives · 959 Views · Jul 19, 2014

Differential Diagnosis of Polycythemia Vera. True / Absolute Polycythemia. Apparent / Relative Polycythemia. Either a decrease in plasma volume (relative polycythemia ) or a misperception of what constitutes the upper limit of normal values for either hemoglobin or hematocrit.

#differential diagnosis of polycythemia vera #differential diagnosis of polycythemia vera ppt #powerpoint #presentation
Differential Diagnosis of Polycythemia Vera - slide 1
01 / 14Differential Diagnosis of Polycythemia Vera
1 / 17

Télécharger la présentation

Differential Diagnosis of Polycythemia Vera
Une image / un lien ci-dessous est fourni (tel quel) pour télécharger la présentation

Politique de téléchargement : le contenu du site vous est fourni TEL QUEL pour votre information et votre usage personnel ; il ne peut être vendu, concédé sous licence ni partagé sur d’autres sites sans l’accord de son auteur.Le contenu vous est fourni TEL QUEL, pour votre information et votre usage personnel uniquement. Téléchargez la présentation en cliquant sur ce lien. Lors du téléchargement, si vous ne parvenez pas à télécharger une présentation, l’éditeur a peut-être supprimé le fichier de son serveur.Pendant le téléchargement, si vous ne parvenez pas à obtenir une présentation, le fichier a peut-être été supprimé par l’éditeur.

F I N

Plus de contenu associé

Transcription de la présentation

  1. Differential Diagnosis of Polycythemia Vera

  2. True / Absolute Polycythemia Apparent / Relative Polycythemia Either a decrease in plasma volume (relative polycythemia) or a misperception of what constitutes the upper limit of normal values for either hemoglobin or hematocrit Either a clonalmyeloproliferativedisorder (polycythemiavera) or a nonclonal increase in red blood cell mass that is often mediated by erythropoietin (secondary polycythemia) Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  3. APPARENT POLYCYTHEMIA • Relative polycythemia • Conditions that cause acute depletion of plasma volume e.g. severe dehydration • The existence of chronic contraction of the plasma volume, such as postulated for: • Gaisböck'ssyndrome – relative polycythemia associated with hypertension and nephropathy • Stress / spurious polycythemia – relative polycythemia associated with emotional stress Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  4. ABSOLUTE / TRUE POLYCYTHEMIA    • Polycythemiavera • Secondary polycythemia • Congenital    • Associated with high or normal serum erythropoietin level    • Associated with low serum erythropoietin level • Acquired    • Erythropoietin mediated • Hypoxia-driven • Hypoxia-independent (pathologic erythropoietin production) • Drug associated • Unknown mechanism Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  5. Secondary Polycythemia • Congenital    • Associated with high or normal serum erythropoietin level    • Associated with low serum erythropoietin level • Acquired    • Erythropoietin mediated • Hypoxia-driven • Hypoxia-independent (pathologic erythropoietin production) • Drug associated • Unknown mechanism Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  6. Secondary Polycythemia • Congenital    • Associated with high or normal serum erythropoietin level    • Associated with low serum erythropoietin level • Acquired    • Erythropoietin mediated • Hypoxia-driven • Hypoxia-independent (pathologic erythropoietin production) • Drug associated • Unknown mechanism Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  7. Secondary Polycythemia: Congenital Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  8. Secondary Polycythemia • Congenital    • Associated with high or normal serum erythropoietin level    • Associated with low serum erythropoietin level • Acquired    • Erythropoietin mediated • Hypoxia-driven • Hypoxia-independent (pathologic erythropoietin production) • Drug associated • Unknown mechanism Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  9. Secondary Polycythemia: Acquired Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  10. Secondary Polycythemia • Congenital    • Associated with high or normal serum erythropoietin level    • Associated with low serum erythropoietin level • Acquired    • Erythropoietin mediated • Hypoxia-driven • Hypoxia-independent (pathologic erythropoietin production) • Drug associated • Unknown mechanism Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  11. Secondary Polycythemia: Acquired Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  12. Secondary Polycythemia • Congenital    • Acquired    • Erythropoietin mediated • Hypoxia-driven • Hypoxia-independent (pathologic erythropoietin production) • Drug associated • Erythropoietin doping • Treatment with androgen preparations    • Unknown mechanism   Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  13. Secondary Polycythemia • Congenital    • Acquired    • Erythropoietin mediated • Hypoxia-driven • Hypoxia-independent (pathologic erythropoietin production) • Drug associated • Unknown mechanism   • Post–renal transplant erythrocytosis Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. Goldman: Cecil Medicine, 23rd ed.

  14. References • Fauci, et al: Harrison’s Principles of Internal Medicine, 17th ed. • Goldman: Cecil Medicine, 23rd ed.