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Engaging Cell Biology Experiments: Making Science Fun & Addictive

This module by Liz Smythe offers third-level students hands-on experience with research laboratory work in cell biology. It focuses on experimental design, protocol development, data interpretation, and presentation in a research environment. The emphasis is on executing and interpreting experimental protocols as practiced in research laboratories, challenging students beyond the standard practical modules with smaller class sizes. Assessment includes a write-up and lab performance evaluation. It encourages students to ask questions freely and engages them in detailed experimental protocols, promoting ownership and a taste for bench work. The unique aspect lies in enabling students to go beyond basic techniques to explore intricate experiments, fostering excitement and addiction towards science. The module aims to provide a profound understanding of what real scientific work entails.

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Engaging Cell Biology Experiments: Making Science Fun & Addictive

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  1. Enabling students to find experiments fun and just a little bit addictive..... Liz Smythe Department of Biomedical Science

  2. BMS385 Practical cell biology Aim: This module aims to provide third level students with experience of research laboratory work in cell biology.

  3. BMS385 Practical cell biology Aim: This module aims to provide third level students with experience of research laboratory work in cell biology. Objectives: By the end of this module students should be able to: *Describe the principles of experimental design and the stages of development of a practical protocol * interpret and present data in a format used in a research environment

  4. BMS385 Practical cell biology Aim: This module aims to provide third level students with experience of research laboratory work in cell biology. Objectives: By the end of this module students should be able to: *Describe the principles of experimental design and the stages of development of a practical protocol * interpret and present data in a format used in a research environment Particular emphasis will be placed on the development, execution and interpretation of experimental protocols as is standard practice in a research laboratory.

  5. What is different about this module?

  6. What is different about this module? Standard practical module: Requirements: Predictable outcome Knowledge of fundamental techniques Logistics of classes with large numbers Isabelle Smythe

  7. Standard practical

  8. Standard practical Problem: what if we need to go back to first principles?

  9. Standard practical Problem: what if we need to go back to first principles? ….or want to try something more elaborate?

  10. …yes we did that in Level 1 but it was set up for us so I didn’t really pay attention…

  11. So what do we do?

  12. So what do we do? • Introduction • The principle of experiment design • hypothesis, • experimental set-up, • data interpretation, • re-evaluation of hypothesis

  13. So what do we do? • Introduction • The principle of experiment design • hypothesis, • experimental set-up, • data interpretation, • re-evaluation of hypothesis • The principle behind the specific experiments

  14. So what do we do? • Introduction • The principle of experiment design • hypothesis, • experimental set-up, • data interpretation, • re-evaluation of hypothesis • The principle behind the specific experiments • What we expect from them three related experiments • outline of protocol for the first

  15. So what do we do? • Introduction • The principle of experiment design • hypothesis, • experimental set-up, • data interpretation, • re-evaluation of hypothesis • The principle behind the specific experiments • What we expect from them three related experiments • outline of protocol for the first • Assessment • 30% for write-up • 70% based on lab performance • (thought, planning, execution, interpretation)

  16. So what do we do? • Introduction • The principle of experiment design • hypothesis, • experimental set-up, • data interpretation, • re-evaluation of hypothesis • The principle behind the specific experiments • What we expect from them three related experiments • outline of protocol for the first • Assessment • 30% for write-up • 70% based on lab performance • (thought, planning, execution, interpretation) • What they can expect from us • to ask as many questions as they wish • (but to expect further questions in response)

  17. The first day This may have been a mistake…………

  18. The first day This may have been a mistake………… ..and it IS fairly chaotic…

  19. As the module progresses….. Proficient Creative Observant Enabled Confident Independent

  20. Practicalities

  21. Practicalities Small numbers

  22. Practicalities Small numbers Feasibility

  23. Practicalities Small numbers Feasibility Demanding!

  24. Practicalities Small numbers Feasibility Demanding! Rewards Students:

  25. Practicalities Small numbers Feasibility Demanding! Rewards Students: Ownership

  26. Practicalities Small numbers Feasibility Demanding! Rewards Students: Ownership Taste for bench work

  27. Practicalities Small numbers Feasibility Demanding! Rewards Students: Ownership Taste for bench work Excitement of science (addiction!)

  28. Practicalities Small numbers Feasibility Demanding! Rewards Students: Ownership Taste for bench work Excitement of science (addiction!) Awareness

  29. Practicalities Small numbers Feasibility Demanding! Rewards Students: Ownership Taste for bench work Excitement of science (addiction!) Awareness Average students can perform very well

  30. Feedback I thought all my University courses would be like this one Module taught me what science is really like… I enjoyed the module because I was treated like an equal

  31. Acknowledgements Thanks to Bruno Orsi, Trinity College, Dublin

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