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What is an Ontology?

What is an Ontology?. An ontology is a specification of a conceptualization that is designed for reuse across multiple applications and implementations. …a specification of a conceptualization is a written, formal description of a set of concepts and relationships in a domain of interest.

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What is an Ontology?

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  1. What is an Ontology? An ontology is a specification of a conceptualization that is designed for reuse across multiple applications and implementations. …a specification of a conceptualization is a written, formal description of a set of concepts and relationships in a domain of interest. Peter Karp (2000) Bioinformatics 16:269

  2. Ontologies in Gene Expression Databases • Controlled vocabulary • May be hierarchical (e.g., taxonomy) • Schema • Concepts as objects or relational tables • Attributes and data types provide specification • Relationships specified through subclassing (objects) or foreign keys (relational tables) • Knowledge representation • Link to other domains (gene sequence annotation, gene and protein roles, pathways) • Facilitate data exchange by mapping common concepts

  3. www.mged.org

  4. MGED Ontology Working Group www.cbil.upenn.edu/Ontology/MGED_ontology.html

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