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Pharmacology Revision Quiz

Pharmacology Revision Quiz. 17/09/12. ACE inhibitors cause the EFFERENT ARTERIOLE of the glomerulus to …………….. This results in …………. blood flow to the kidneys Therefore ACE inhibitors are contra-indicated in those with…………. Contra-Indications. ………….. ………….. ………….. …………. Side Effects.

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Pharmacology Revision Quiz

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  1. Pharmacology Revision Quiz 17/09/12

  2. ACE inhibitors cause the EFFERENT ARTERIOLE of the glomerulus to …………….. This results in …………. blood flow to the kidneys Therefore ACE inhibitors are contra-indicated in those with………….

  3. Contra-Indications • ………….. • ………….. • ………….. • …………..

  4. Side Effects • …………….. • …………….. • …………….. • …………….. • ……………..

  5. Which of the following chemical components of the blood is mainly responsible for transporting exogenous (dietary) triglyceride from the intestine following a meal?

  6. Acetyl-CoA + Acetoacetyl-CoA HMG-CoA HMG-CoA reductase Mevalonate Isopentenyl Farnesyl Squalene Ianosterol CHOLESTEROL

  7. Side Effects • …………….. • …………….. • …………….. • ……………...

  8. A man was diagnosed with type 2 diabetes around two years ago and started metformin and simvastatin shortly after diagnosis. He is very concerned about the risk of developing side effects from his statin and asks you to discuss this with him at length. What risk factor might increase his likelihood of developing rhabdomyolysis?

  9. Mechanism of Action Leukotrienes Lipo-oxygenase Thromboxane Phospholipids Arachidonic acid Tx Synthase Phospholipase A2 COX Prostaglandin A2 PG Synthase Prostaglandins

  10. Gastric Side Effects • PG E-2 …………. gastric acid secretion. • PG E-2 ………….. gastric mucus secretion. • If prostaglandins are inhibited, gastric acid secretion………..and gastric mucus secretion ……………... • This may lead to ……………………….formation.

  11. Contra-Indications • ………….. • ………….. • ………….. • …………..

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