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The Endocrine System. ˈen- də - krən , -ˌ krīn , . Key words. Excess – hyper- too much example hyperthyroidism Deficiency- hypo-too little example hypothyroidism Inhibit- to reduce or suppress the activity of example carbimazole to treat hyperthyroidism
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The Endocrine System \ˈen-də-krən, -ˌkrīn, \
Key words • Excess – hyper- too much example hyperthyroidism • Deficiency- hypo-too little example hypothyroidism • Inhibit- to reduce or suppress the activity of example carbimazole to treat hyperthyroidism • Replacement therapy: therapy involving the supplying of something lacking from or lost to the system example injection of insulin in the treatment of Type 1 diabetes
Negative feedback systems • 1-TRH(Thyrotrophin-releasing hormone ) is secreted in the hypothalamus and triggersthe production of TSH(thyroid-stimulating hormone) in the pitutary. • 2-TSH stimuatesthe TSH receptor in the thyroid to increase synthesis of both T4(thyroxine) and T3(triiodothyronine)and also to release stored hormone,producing increased plasma levels of T4 and T3. • 3-T3 feeds back on the pituitary and perhaps the hypothalamus to inhibit TRH and TSH secretion
