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ABO System. H gene Se gene AB genes. L – Fucose N –acetyl galactosamine Galactose N-acetylglucosamine. ABO Blood Group Antigens. A. NAG. Gal. NAcGA. Fuc. H. A antigen. NAG. Gal. NAG. Gal. B antigen. Fuc. Precursor oligosaccharide. H antigen. Gal. Gal. NAG.
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ABO System • H gene • Se gene • AB genes
L – Fucose • N –acetyl galactosamine • Galactose • N-acetylglucosamine
ABO Blood Group Antigens A NAG Gal NAcGA Fuc H A antigen NAG Gal NAG Gal B antigen Fuc Precursor oligosaccharide H antigen Gal Gal NAG NAcGA (N-acetylgalactoseamine) Gal (galactose) B Fuc
ABO Blood Group Reactivity blood group genotypes antigens antibodies to (phenotype) ABO in serum A AA, AO A anti-B B BB, BO B anti-A AB AB A and B none O OO H anti-A/B O hh none anti A,B,H
روشهای انجام گروه خون • Direct method (cell type) Unknown RBC + anti A ,anti B • Indirect method (back type) A cell , B cell + unknown serum
Rh system • D ,C,c,E,e genes DCe / c E DCE / ce Ce / CE Dce / DCE Cell type RBC + anti D