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human CycK -580aa 1 mkenkenssp svtsanldht kpcwywdkkd lahtpsqleg ldpatearyr regarfifdv

Blazek_Fig S1. human CycK -580aa 1 mkenkenssp svtsanldht kpcwywdkkd lahtpsqleg ldpatearyr regarfifdv 61 gtrlglhydt latgiiyfhr fymfhsfkqf pr YVTGACCL FLAGK veetp kkckdiikta 121 r SLLNDVGFG GFGDDPK eev mvlerillqt ik FDLQVEHP YQFLLK yakq lkgdknkiqk

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human CycK -580aa 1 mkenkenssp svtsanldht kpcwywdkkd lahtpsqleg ldpatearyr regarfifdv

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  1. Blazek_Fig S1 human CycK-580aa 1 mkenkenssp svtsanldht kpcwywdkkd lahtpsqleg ldpatearyr regarfifdv 61 gtrlglhydt latgiiyfhr fymfhsfkqf prYVTGACCL FLAGKveetp kkckdiikta 121 rSLLNDVGFG GFGDDPKeev mvlerillqt ikFDLQVEHP YQFLLKyakq lkgdknkiqk 181 lvqmawtfvn dslcttlslq wepeiiavav mylagrlckf eiqewtskpm yrrwweqfvq 241 dvpvdvledi chqildlysq gkqqmphhtp hqlqqppslq ptpqvpqvqq sqpsqsseps 301 qpqqkDPQQPAQQQQPAQQPKpspqpssp rqvkrAVVVS PKEENKaaep pppkipkiET 361 THPPLPPAHPPPDRkpplaa algeaeppgp vdatdlpkvq ipppahpapv hqppplphrp 421 pppppssymt gmsttssyms gegyqslqsm mktegpsyga lppaygppah lpyhphvypp 481 npppppvppp pasfpppaip pptpgypppp ptynpnfppp pprlppthav pphpppglgl 541 ppasypppav ppggqppvpp pipppgmppv gglgraawmr A

  2. Blazek_Fig S1 B

  3. Blazek_Fig S1 cont. B

  4. Blazek_Fig S2 Cdk12-GFPCdk13-Cherrydapimerge A

  5. Blazek_Fig S2 CycK CycK Cdk12-Flag Cdk13-Flag actin actin 1 2 3 4 5 6 B

  6. Blazek_Fig S3 A

  7. Blazek_Fig S3 B

  8. Blazek_Fig S3 r=0.64 C

  9. Blazek_Fig S3 18 14 Frequency (%) 10 6 2 0 500 100 300 Gene size (kb) D

  10. Blazek_Fig S3 20 15 Frequency (%) 10 5 0 50 100 Number of exons E

  11. Blazek_Fig S3 F

  12. Blazek_Fig S4

  13. Blazek_Fig S5 siRNA C siRNA CycK siRNA Cdk12 Number of cells Number of cells Number of cells DNA content DNA content DNA content

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