Comprehensive Analysis of SV40 Promoter and 3' UTR Variants on Luciferase Expression

DESCRIPTION

This study explores the various configurations of the SV40 promoter and 3’ UTR, assessing their effects on luciferase expression. By analyzing sequences such as Wt (+1/+2743), and other segment combinations like (+1/+937) and (+1/+1015), we delve into the regulatory mechanisms at play. This research lays the groundwork for understanding promoter functionality and post-transcriptional regulation in gene expression studies. Findings could have implications in genetic engineering and therapeutic applications.

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Dec 25, 2025

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Comprehensive Analysis of SV40 Promoter and 3' UTR Variants on Luciferase Expression

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1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 SV40 promoter Luciferase 3’-UTR Wt (+1/+2743) (+1/+937 - +1015/+2743) (+1/+2518) (+1/+937 - +1015/+2518) (+1/+1325) (+1075/+2518) (+1/+820) (+1/+313) (+859/+1171) (+859/+937 - +1015/+1171) (+859/+1010) (+859/+983) (+859/+954) (+859/+932) (+896/+1010) (+933/+1171) (+956/+1171) (+984/+1171) (+1011/+1171) (+933/+1030) (+933/+1010)