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Pathophysiology

Pathophysiology. Concepts and Terms. pathos physio- -ology iatro- idio- gno- syn-, sym- -genesis -itis -oma carcin- neo- -plasia dia- pro- hyper- meta-. Medical Words Physiology Pathophysiology Pathogenesis Iatrogenic Idiopathic Diagnosis Prognosis Carcinoma Neoplasia

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Pathophysiology

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  1. Pathophysiology Concepts and Terms

  2. pathos physio- -ology iatro- idio- gno- syn-, sym- -genesis -itis -oma carcin- neo- -plasia dia- pro- hyper- meta- Medical Words Physiology Pathophysiology Pathogenesis Iatrogenic Idiopathic Diagnosis Prognosis Carcinoma Neoplasia Hyperplasia Metaplasia Organ + itis Hepatitis Gastroenteritis Nephritis Mastitis Encephalitis Dermatitis Bronchitis Valvuloendocarditis Osteitis Otitis Appendicitis Thyroiditis Cystitis Medical Terminology

  3. Holistic View • Health vs. Disease • Wellness Model (health focus) • Awareness • Education • Growth • Treatment Model (disease focus) • Signs • Symptoms • Disability • Death

  4. System Organization • Levels • Body Cavities • Major Divisions • Organ Location

  5. Homeostasis • Define • Major Systems • Communication

  6. Feedback • Define • Types • Examples

  7. Disease Process • 5 Components • Epidemiology • Etiology • Pathophysiology • Clinical Manifestations • Outcome “COPE”

  8. Epidemiology • Epidemiology • Define • Factors: Predisposing, Precipitating • Related Terms • Incidence • Prevalence • Morbidity • Mortality • Endemic • Epidemic • Pandemic Herpes D Virus

  9. CDC Reportable Diseases (examples) • Viral /Bacterial • HIV • Anthrax • Influenza • Pertussis, Diptheria • TB, Leprosy • Botulism, Tetanus • Hepatitis • E. coli, Samonella, Shigella • STDs • Cholera • Mumps, Measles, Rubella • Legionella • Small Pox • Tularemia • Toxic Shock • Leptospirosis • Vector Borne • Lyme • Plague • RMSF • Ehrlichia • Malaria, Yellow Fever • Zoonotic • Rabies • Brucellosis • Cryptosporosis • Toxoplasmosis

  10. Major Etiologic Categories • Genetic • Sickle Cell Anemia • CF • MD • Hemophilia A • Acquired • Infectious • Traumatic • Iatrogenic • Nosocomal • Multifactoral • CAD • DM • Cancer • Congenital Heart Disease • Hypertension • Emphysema

  11. Pathophysiology Focus • Disease Mechanisms • Genetic • Internal • External • Pathogenesis • Morphology • Gross • Histological

  12. Various Classification of Disease • Anatomical • Organ • System • Developmental (age) • Neonatology • Pediatrics • Adolescent • Adult • Geriatrics • Etiological

  13. Etiology, DAMNIT ! • D = Degenerative, Developmental • A = Anomaly, Accident, Autoimmune • M = Metabolic, Mechanical, Mental • N = Neoplasia, Nutrition, Neurological • I = Infectious, Immune, Iatrogenic, Idiopathic, Inherited, Inflammatory, Ischemic • T = Trauma, Toxins, Toxcities

  14. My Possible Problem List • Location • Gross • Histological • Physiological • Remember: DAMNIT

  15. Clinical Manifestations • Symptoms /Syndrome • Patient Report • Subjective • Related Terms: Prodromal, Insidious, Latent • Signs • Health care exam • Observable phenomena • Objective • Diagnostic Criteria • Laboratory results • Imaging • Biopsy Digital Thermal Imaging

  16. Outcome • Expected • Prognosis • Actual • Cure • Remission • Exacerbation • Complication • Sequella • Palliative • Death

  17. SOAP • S • O • A • P

  18. Stress • Define • Stressor examples • Positive • Negative • Types • Major • Minor • Symptoms • GAS • Alarm (ANS) • Resistance (H-P-A axis) • Exhaustion (+ feedback)

  19. Stress Related Disorders • Immune: Autoimmune, Neoplasia • Cardiovascular: HT, CAD, Dysrhythmias • Respiratory: Asthma, URTI, TB • Renal: Interstitial cystitis • Neurologic: Depression, MS, Headache • GI: Diarrhea, IBS, Eating Disorders • Endocrine: DM, Hyperthyroidism • Reproductive: Infertility • Musculoskeletal: RA, SLE, Chronic Fatigue • Integumentary: Eczema, Acne, Urticaria, Herpes

  20. Adaptation • Define • AKA • Compensatory mechanisms • Homeostatic Mechanisms • Control Systems • Regulatory systems • Homeostatic Control and Feedback • Limits • Energy use • Efficient (overshoot, undershoot) • Effective (prolonged response  change feedback)

  21. De-stress • Sleep • Exercise • Diet • Medical Check-ups • Energy • Attitude Stressed is Desserts spelled backwards

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