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Connective Tissue Types Cartilage

Connective Tissue Types Cartilage. Dr. Jack L. Haar Department of Anatomy Sanger Hall 9-064. Cartilage General considerations Light, flexible, much intercellular substance Forms quickly Nutrients supplied by diffusion, no blood vessels. B. Embryology Forms very early in development.

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Connective Tissue Types Cartilage

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  1. Connective Tissue TypesCartilage Dr. Jack L. Haar Department of Anatomy Sanger Hall 9-064

  2. Cartilage • General considerations • Light, flexible, much intercellular substance • Forms quickly • Nutrients supplied by diffusion, no blood vessels

  3. B. Embryology Forms very early in development

  4. Histological components • Cells • Chondroblasts • Come from mesenchymal cells or multipotential C.T. cells • Differentiate to produce cartilage matrix

  5. Chondrocyte (mature cartilage cell)Located in lacunaeGolgi, rER , fat droplet possible

  6. Intercellular matrixFiber type depends on type of cartilageGround substance, mainly chondroitin sulfateTerritorial and interterritorial matrix

  7. Perichondrium • Fibrous layer of dense C.T. • Chondrogenic layer of chondroblasts

  8. Perichondrium (cartilage is non-vascular)

  9. Growth of cartilage • Appositional • Interstitial

  10. Types of cartilageHyaline Cartilage – type II collagen Distribution: nose larynx, strachea, bronchi

  11. Elastic Cartilage • Abundant elastic fiber • Branching network • Limited ground substance

  12. Distribution • External ear, epiglottis, part of the larynx

  13. Fibrocartilage • “Never occurs alone but blends insensibly with neighboring hyaline cartilage, fibrous tissue or bone” • Fiber component • Bundles of collagen type I fibers fill matrix • Chondrocytes • May appear in parallel rows or randomly distributed • Occur in lacunae • Minimal ground substance • Function: strength and transition

  14. Function:Provides stiffness and great tensile strength at tendon insertions

  15. Function: A transition form from dense FECT and cartilage, provides shock absorption

  16. DistributionIntervertebral disc Annulus fibrosus Nucleus pulposus

  17. DistributionPubic symphysis Tendons to bones

  18. Regressive changes in cartilagea.Chondrocytes greatly hypertrophy, produce alkaline phosphatase, a calcifiable matrix; b. Calcium phosphate is deposited in matrix; does not allow diffusion of nutrients c. Chondrocytes die leaving behind the calcified matrix

  19. Occurrencea. In some cartilage as it ages b. As early stage of bone production

  20. http://www.path.uiowa.edu/virtualslidebox/ Table of Contents Supporting tissue and muscle Hyaline cartilage #5 Elastic cartilage #7http://java.vcu.edu/som-histology/

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