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Advancements in Computational Models for Brain Vasculature Physics

This presentation by Brian Sweetman, conducted at the LPPD Group Seminar on May 28, 2010, explores recent advances in computational models aimed at understanding brain vasculature. The discussion highlights the significance of mesh refinement on the distribution of terminals, with a comparison between grid-based and non-grid simulations. Key findings include improved outcomes in vessel cluster distribution using optimized mesh grids. Additionally, ongoing projects and future goals emphasize the collaborative efforts in generating vascular trees, studying vessel-tissue interactions, and completing a revised spinal canal research paper.

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Advancements in Computational Models for Brain Vasculature Physics

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  1. Computational models for brain physics: research update Presenter: Brian Sweetman Date: May 28, 2010 LPPD Group Seminar, May 28, 2010

  2. Cerebral Vasculature LPPD Group Seminar, May 28, 2010

  3. Computer models of vasculature LPPD Group Seminar, May 28, 2010

  4. CCO results in confined mesh LPPD Group Seminar, May 28, 2010

  5. Grid vs. No Grid LPPD Group Seminar, May 28, 2010

  6. Effect of Mesh Refinement-300 Terminals each LPPD Group Seminar, May 28, 2010

  7. Better distribution with mesh grid; no clustering in center Current; no clustering Prior outcome with clustering LPPD Group Seminar, May 28, 2010

  8. Better distribution with mesh grid; no clustering in center 1000 terminals 2000 terminals LPPD Group Seminar, May 28, 2010

  9. Semester Goals 1: Submit 3D Spinal Canal paper (Complete) -Now under 2nd review 2: Preliminary Exam (Complete) 3: Present at UIC Research Forum (Complete) 4: Generate vascular trees using CCO algorithm (Complete and in progress) 5: 2D Vasculature-brain tissue interaction code with Alex; article? (not complete) LPPD Group Seminar, May 28, 2010

  10. Summer Plan • Work with Alex on vessel-tissue interaction • Work with Nicholas on developing mesh-based vasculature trees and running steady-state simulations • Work with Andrej on implementing constrained optimizer to avoid “very small” segments • Finalize paper with Michalis; submit revised version by Aug 24. LPPD Group Seminar, May 28, 2010

  11. LPPD Group Seminar, May 28, 2010

  12. Grid vs. No Grid LPPD Group Seminar, May 28, 2010

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