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DAPT

Boc Sciences offers cas 208255-80-5 DAPT in bulk,please inquire us to get a quote for 208255-80-5 DAPT.<br>https://www.bocsci.com/dapt-cas-208255-80-5-item-101748.html<br>

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DAPT

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  1. DAPT - CAS 208255-80-5 Catalog number: B0084-101748 Category: Inhibitor Please be kindly noted products are not for therapeutic use. We do not sell to patients. Molecular Formula C23H26F2N2O4 Molecular Weight 432.46 COA Inquire Targets Amyloid-β | γ-secretase Description DAPT, also called γ-Secretase Inhibitor IX, is a potent and selective inhibitor of γ- secretase which leads to a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (total Aβ: IC50 = 115 nM (human); Aβ42: IC50 = 200 nM (human)). Ordering Information Order Now Bulk Inquiry Publication citing BOC Sciences Products 1.Development and comparison of gas chromatography–mass spectrometry techniques for analysis of flame retardants 2.An I436N substitution confers resistance of influenza A (H1N1) pdm09 viruses to multiple neuraminidase inhibitors without affecting viral fitness 3.Treatment with a nucleoside polymerase inhibitor reduces shedding of murine norovirus in stool to undetectable levels without emergence of drug-resistant variants 4.Oleanolic Acid Promotes Neuronal Differentiation and Histone Deacetylase 5 Phosphorylation in Rat Hippocampal Neurons

  2. 5.Effect of long-term dietary sphingomyelin supplementation on atherosclerosis in mice 6.Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease >> More Specification Properties Reference Reading    Brife Description Reduces Aβ42 levels; γ-secretase inhibitor; Total Aβ: IC50 = 115 nM (human); Aβ42: IC50 = 200 nM (human) Appearance White solid Synonyms tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2- phenylacetate; dapt; 208255-80-5; DAPT (GSI-IX); gamma-Secretase Inhibitor IX; CHEBI:86193; MFCD04974585; DAPT, GSI-IX; InSolution™ gamma-Secretase Inhibitor IX; N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester; N-[(3,5- Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester(DAPT); C23H26F2N2O4; GSIIX; S2215_Selleck; AC1NSKCB; PubChem22436; GSI-IX; DAPT,GSI- IX; DAPT; DAPT - GSI-IX; MLS006010075; CHEMBL255682; QCR-29; SCHEMBL1360313; DTXSID00415519; AOB33372; DAPT-Supplied by Selleck Chemicals; EBD16444; ZINC1549363; ABP000317; ZINC01549363; AKOS024457209; CS-0264; NCGC00167803- 03; (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu; AC-23163; AK477268; BC649954; CJ- 24363; HY-13027; KB-57235; SMR004701228; AB0033805; LS-191073; D4257; GSI-IX, 208255-80-5; X7572; W-5319; AB01566837_01; GSI-IX , GSI IX; 208255-80-5; N-[N- (3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester; DAPT|N-[(3,5- Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[(3,5- Difluorophenyl)acetyl]-[l-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[N-(3,5- difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester Solubility Soluble to 15 mg/mL in DMSO, to ~1 mg/mL in ethanol, in dichloromethane, to ~25 mg/mL in DMF, and to ~0.1 mg/mL in 1:9 solution of DMF:PBS(pH 7.2) Storage Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -24℃ for long term (months to years). MSDS Inquire

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