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DAPT Duration in PCI: The Art of Medicine When the Science Might Not Exist

DAPT Duration in PCI: The Art of Medicine When the Science Might Not Exist. European and US Guidelines. European and US Guidelines. “Optimal” DAPT Duration and DES Revascularization A Less than “Optimal” Evidence Basis. Long-Term DAPT: Bleeding Risk. PRODIGY: 2-Year Death/MI/Stroke.

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DAPT Duration in PCI: The Art of Medicine When the Science Might Not Exist

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  1. DAPT Duration in PCI: The Art of Medicine When the Science Might Not Exist

  2. European and US Guidelines

  3. European and US Guidelines

  4. “Optimal” DAPT Duration and DES RevascularizationA Less than “Optimal” Evidence Basis

  5. Long-Term DAPT: Bleeding Risk

  6. PRODIGY: 2-Year Death/MI/Stroke

  7. PRODIGY: 2-Year BARC 2, 3, or 5 Bleeding

  8. PRODIGY: Outcomes Relative to Stent Type and DAPT Duration

  9. PRODIGY: Outcomes Relative to Stent Type and DAPT Duration

  10. PRODIGY: Outcomes Relative to Stent Type and DAPT Duration

  11. REAL-LATE/ZEST-LATE: 2-Year End Points

  12. RCT Sample Size Calculations (6 mo vs 12 mo)Delta, Event-free Duration, Time to End Point Influence (N)

  13. DAPT Trial: Total Enrollment

  14. Pooled Xience EES AnalysisTiming of First DAPT Interruption and ST Through 1 Year

  15. RESOLUTE Pooled DAPT Interruption AnalysisTiming of First DAPT Interruption and ST Through 1 Year

  16. RESOLUTE Pooled DAPT Interruption AnalysisTiming of First DAPT Interruption and ST Through 1 Year

  17. Global Leaders

  18. WOEST1-Year Outcomes: ASA/Clopidogrel/Warfarin vs Clopidogrel/Warfarin

  19. DAPT Trial Randomization Rates

  20. Conclusions

  21. Conclusions (cont)

  22. Conclusions (cont)

  23. Conclusions (cont)

  24. 双重抗血小板治疗的合适使用时间及如何合理应用

  25. 展望

  26. Spanish Perspective

  27. Recommendation for 12 Months of DAPT After DES Implantation

  28. Recommended Duration of DAPT After PCI

  29. Discontinuation of Antiplatelet Therapy as Predictor of Stent Thrombosis

  30. Pipeline: RCT on DAPT After Stenting

  31. EES vs PES: 1-Year Meta-Analysis (n = 6683)

  32. References

  33. References (cont)

  34. References (cont)

  35. Abbreviations

  36. Abbreviations (cont)

  37. Abbreviations (cont)

  38. Abbreviations (cont)

  39. Abbreviations (cont)

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