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The CTSA at the University of Pennsylvania

The CTSA at the University of Pennsylvania. Structural background General approach New community engagement programs initiated. Spectrum of Clinical Research.

bradley-summers
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The CTSA at the University of Pennsylvania

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  1. The CTSA at theUniversity of Pennsylvania • Structural background • General approach • New community engagement programs initiated

  2. Spectrum of Clinical Research The diagram below is designed to demonstrate visually the different approaches available in clinical research, relationships among the different approaches, and the relationships among clinical research approaches, bench research, and public health. Clinical Research Patient Oriented Research Translational Research (Proof of Concept) Translational Research (Proof in Practice) Public Health and Bioethics Proof of Concept Animals Large Randomized and Observational Trials Epidemiology Proof of Concept Humans Health Services Research Bench Research This diagram is based on the report written by members of the Clinical Research Roundtable of the Institute of Medicine and published in the March 12, 2003 issue of JAMA.

  3. Previous Structures at Penn • Institute for Translational Medicine and Therapeutics (ITMAT) • Center for Clinical Epidemiology and Biostatistics (CCEB)

  4. Previous Structures at Penn: ITMAT • Institute for Translational Medicine and Therapeutics • “supports research at the interface of basic and clinical research, with a particular focus on the development of new and safer therapeutic entities.” • $3 million/year of institutional funds • 10 primary faculty, with plans for rapid growth

  5. Center for Clinical Epidemiology and Biostatistics:Organizational Chart

  6. Penn CTSA • Led by ITMAT • PI: Garret FitzGerald • Co-PIs: Peter Adamson, Glen Gaulton, Dan Rader, Brian Strom • Incorporates HUP and CHOP GCRCs • Joint proposal from Penn’s Schools of Med, Nsg, Dentistry, Edn, Arts & Sciences, Vet, Engineering, Annenberg, and Wharton; plus Children’s Hospital of Philadelphia, Wistar Institute, & Univ of the Sciences in Phila

  7. Penn CTSA CommunityEngagement Plans-1 1. To partner with the University of Pennsylvania’s Center for Community Partnerships; 2. To partner with the School of Medicine’s Office of Diversity and Community Outreach; 3. To include members of the West Philadelphia community (probably a patient or family member of a patient) on the Translational Research Center Council; 4. To foster our performance of community-based participatory research, including assessing the health needs of the community and funding community-based participatory research projects;

  8. Penn CTSA CommunityEngagement Plans-2 5. Through partnership with the Leonard Davis Institute and the Wharton School, to develop a new Dissemination Core, to reach out to policymakers nationwide; 6. Use of UPHS and CHOP web pages to publicize clinical trials; 7. To develop a new Core in Community Outreach using Health System Informatics, which will enhance subject recruitment, allow for evaluation of new types of medical practice, and facilitate the application of translational discoveries into the community;

  9. Penn CTSA CommunityEngagement Plans-3 8. To develop a new core for Automated Claims and Medical Record Databases; 9. Educational changes in the MSCE program, to foster its community focus

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