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Exclusive Proteins of Chromosome 16: Insights from 24 Experiments with FDR 1%

This project presents an in-depth analysis of exclusive proteins located on chromosome 16, derived from 24 experiments with a 1% false discovery rate (FDR) at the peptide level. A total of 537 proteins and 385 exclusive genes were identified. Notable findings include both the 5 most abundant and less abundant proteins, such as CHD9, CBP, and ALDOA. The study highlights quantitative information pertaining to these proteins and explores the relationship between protein levels and experiment number, providing valuable insights into protein distribution and function on chromosome 16.

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Exclusive Proteins of Chromosome 16: Insights from 24 Experiments with FDR 1%

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  1. A.M. 30/11/2012 HPP – Shotgun Status

  2. Project 22/8

  3. FDR 1%: Proteinlevel

  4. Peptides & proteinsbylabs

  5. Proteinsbyexperiment

  6. Exclusive Proteins (includingsecretome)

  7. Chr16 - distribution Prot: 537 Genes: 385

  8. Exclusive proteins Chr16

  9. FDR 1% at peptidelevelfrom24 experiments

  10. FDR 1% at peptidelevelfrom 24 experiments

  11. Exclusive Proteins

  12. Exclusive Proteins of chromosome 16

  13. Proteinincreasewithexperimentnumber

  14. Quantitativeinformation? Onlyforchromosome 16 proteins Q = # peptides/kDa

  15. Quantitativeinformation? • 5 Lessabundantproteins of chromosome 16 • CHD9_HUMAN Chromodomain-helicase-DNA-bindingprotein • CBP_HUMAN CREB-bindingprotein • Isoform3 of Dynein heavy chain 3, axonemal • RBBP6_HUMAN Isoform 3 of E3 ubiquitin-protein ligase RBBP6 • ZN646_HUMAN Zinc fingerprotein646 • 5 Mostabundantproteins of chromosome 16 • RS2_HUMAN 40S ribosomalprotein S2 • RS15A_HUMAN 40S ribosomalprotein S15a • COTL1_HUMAN Coactosin-likeprotein • ELOB_HUMAN Transcriptionelongation factor B polypeptide 2 • ALDOA_HUMAN Fructose-bisphosphatealdolaseA

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