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EVALUAREA SISTEMULUI ENDOCRIN

EVALUAREA SISTEMULUI ENDOCRIN. HORMONII A. TESTE DIRECTE DOZARE HORMONI/CATABOLITI TESTE DE STIMULARE/SUPRESIE EVALUARE ANATOMICA.  liberine hipotalamice   hormoni tropi hipofizari   hormonii glandei endocrine

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EVALUAREA SISTEMULUI ENDOCRIN

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  1. EVALUAREA SISTEMULUI ENDOCRIN

  2. HORMONII A. TESTE DIRECTE • DOZARE HORMONI/CATABOLITI • TESTE DE STIMULARE/SUPRESIE • EVALUARE ANATOMICA

  3. liberine hipotalamice hormoni tropi hipofizari hormonii glandei endocrine • hormoni tropi hipofizari hormonii glandei endocrineliberine hipotalamice • hormonii glandei endocrineliberine hipotalamice hormoni tropi hipofizari • liberine hipotalamice hormoni tropi hipofizari hormonii glandei endocrine • hormoni tropi hipofizari hormonii glandei endocrineliberine hipotalamice • hormonii glandei endocrineliberine hipotalamice hormoni tropi hipofizari

  4. TULBURARI DE REGLARE- independent de reglarea hipotalamo-hipofizara • Ex. • Insulina ~ utilizatorul de glucoza/glicemie • Insuficienta pancreaticahipoinsulinismscade glicoliza hepatica hiperglicemie • Insuficienta hepatica scade glicoliza hepatica hiperglicemie stimulare pancreatica hiperinsulinism • Tumori insulinosecretante/hiperaminoacidemiihiperinsulinismhipoglicemie

  5. OBS.!!! 1. interrelaţie Sistemul endocrin, sistermul nervos, sistemul imun. 2. efecte combinate = hormonii se leaga şi de receptorii altor hormoni 3. fenomenul desaturaţie =  hormoni   numarului de receptori  hormoni  numarului de receptori.

  6. B. TESTE INDIRECTE = EFECTELE HORMONILOR

  7. 2. TULBURARILE PROTEINELOR TRANSPORTATOARE •  sintezei/afinitatii proteinelor transportoare =>  hormonii transportati la celule ţinta => efectul hormonilor • sintezei/afinitatii proteinelor transportoare => hormonii totali prin hormonilor legati +hormonii liberi (care determina efectul) => efectul hormonilor

  8. 3. TULBURARILE RECEPTORILOR • numărului/sensibilitatii/anomalii morfo-functionale ale receptorilor =>  efectului hormonilor => liberine, hormoni tropi, hormonii • afinitatea receptorilor => efectul hormonilor

  9. Obs.!!! • În hipo/hipertiroidism dacă  TSH (TSH favorizează dezvoltatea tiroidei) guşa • În hipertiroidism apar autoanticorpi anti-fibre musculare striate ale globului ocular  inflamaţie localăexoftalmie.

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