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Health Effects of Environmental Agents. ENVR430 (Formerly ENVR130) http://www.unc.edu/courses/2006fall/envr/430/001/ Monday Wednesday Friday, 1 to 1:50 pm McGavran-Greenberg 1301 Course director, L.M. Ball lmball@unc.edu , 6-7306. Environmental Health.
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Health Effects of Environmental Agents • ENVR430 (Formerly ENVR130) • http://www.unc.edu/courses/2006fall/envr/430/001/ • Monday Wednesday Friday, 1 to 1:50 pm • McGavran-Greenberg 1301 • Course director, L.M. Ball lmball@unc.edu, 6-7306
Environmental Health Environmental Health comprises those aspects of human health, including quality of life, that are determined by interactions with physical, chemical, biological and social factors in the environment. It also refers to the theory and practice of assessing, correcting, controlling and preventing those factors in the environment that may adversely affect the health of present and future generations. Pew Environmental Health Commission
National Environmental Health Association NEHAwww.neha.org National Center for Environmental Health NCEH www.cdc.gov/nceh/default.htm National Institute for Environmental Health Sciences NIEHS www.niehs.nih.gov
Environmental Scientists and Specialists Conduct research or perform investigations for the purpose of identifying, abating or eliminating sources of pollutants or hazards that affect either the environment or the health of the population. Utilizing knowledge of various scientific disciplines may collect, synthesize, study, report, and take action based on data derived from measurements or observations of air, food, soil, water and other sources U.S. Department of Labor
Environmental Agents • Microbial • Chemical • Physical
Heat Cold Trauma Radiation Ionizing radiation (radioactivity) Non-ionizing radiation X-rays UV Infrared Microwave Radio Electromagnetic Physical Hazards
Chemical Hazards • “Naturally-Occurring” • “Anthropogenic”
Naturally-Occurring Chemicals • Microbial toxins • Bacterial toxins • Botulinus toxin (Clostridium botulinum ) • Shigatoxin (Shigella dysenteriae ) • Fungal toxins (mycotoxins) • Ergot alkaloids (Claviceps purpurea) • Aflatoxins (Aspergillus spps)
Plant Constituents • Alkaloids • Atropine • Solanine • Pigments • Methane • Terpenes • Urushiol Atropine
Animal Constituents • Alkaloids • Snake venom • Ciguatoxin
Combustion Products • Gases • Hydrocarbons • Polycyclic aromatic hydrocarbons Phenanthrene Benzanthracene Benzo[a]pyrene
Minerals • Soil dust (including e.g. Ca, Al, Si) • Leaching into groundwater • Selenium • Arsenic
Anthropogenic Chemicals • Inadvertent introduction • Deliberate use
Inadvertent introduction • Industrial by-products • Insulators • Effluents • Wastes • Spills • Improper disposal
Aromatic hydrocarbons Chlorinated hydrocarbons Industrialsolvents
Drinking water disinfection by-products • Trihalomethanes • Chloroform CHCl3 • Bromodiloromethane CHBrCl2 • Dibromochloromethane CHBr2Cl • Bromoform CHBr3 • Haloacetic acids • Trichloroacetic acid CCl3-COOH • Dichloroacetic acid CHCl2-COOH • Dibromoacetic acid CHBr2-COOH
Combustion products • Gases: CO, CO2, O3, peroxyacyl nitrates, nitrogen oxides (N2O, NO, NO2), sulfur oxides (SO2, SO3) • Particulate matter • Hydrocarbons • Polycyclic aromatic hydrocarbons
Deliberate use • Pesticides • Fertilizers • Food additives • Plasticizers • Pharmaceuticals • Waste disposal
Insecticides • Chlorinated hydrocarbons • Organophosphates • Carbamates
Herbicides • Broad-spectrum • Broad-leaf • Grassy-leaf
Fertilizers • Nitrates • Phosphates
Food additives • Anti-oxidants • Anti-microbials • Sweeteners • Other flavoring agents • Coloring agents • Humectants • Anti-caking agents
THE MICROBIAL WORLD: • SIZES OF MICROBES VIRUS 0.1 um BACTERIUM 1 x 2 um