channery
Uploaded by
17 SLIDES
322 VUES
170LIKES

Proposed Changes to Hemoglobin and Donation Interval Criteria for Whole Blood Donors

DESCRIPTION

This document explores the potential impacts of altering hemoglobin (Hb) and donation interval criteria for whole blood donors. Specific changes proposed include raising the minimum Hb level to 13.0 g/dL for men and 12.0 g/dL for women, alongside adjusting the donation interval from 8 weeks to 12 weeks for men and 16 weeks for women. Analysis of past donor data suggests these changes may minimally affect overall collections, but modifications to donation frequency could significantly hinder donor participation and total blood collections.

1 / 17

Télécharger la présentation

Proposed Changes to Hemoglobin and Donation Interval Criteria for Whole Blood Donors

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

Playing audio...

  1. Proposed changes to hemoglobin and donation interval criteria for whole blood donors:Projected impact on current donor base Anne Eder, MD PhD Executive Medical Officer Blood Products Advisory Committee Meeting July 27, 2010

  2. Four Questions • What would be the impact of changing the minimum predonation Hemoglobin (Hb) from 12.5 g/dL… • …to 13.0 g/dL for men? …to 13.5 g/dL for men? 2. …to 12.0 g/dL for women? • What would be the impact of changing the interdonation interval from 8 weeks (about 6-7 times per year) ….. • ….to 12 weeks (about 4-5 times per year) for men? • ….to 16 weeks (about 3-4 times per year) for women?

  3. Balance Sheet

  4. American Red Cross, 2010 Annual Data – (Denominator) 6 M Red Cells 1.7 M Plasma Products 850,000 Apheresis Platelets 250,000 WB-derived Platelets 40,000 Pooled Platelets Puerto Rico

  5. Hb Distribution, Presenting Donors Male Female NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II) New England Region, ARC, 2008-2009

  6. Question 1: Minimum Hb for Men • Hb 12.5 →13.0 g/dL for men • Hb 12.5 →13.5 g/dL for men *NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II) New England Region, ARC, 2008-2009

  7. Question 2: Minimum Hb for Women • Hb 12.5 →12.0 g/dL for women *NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II) New England Region, ARC, 2008-2009

  8. Questions 1&2: Minimum Hb

  9. Questions 3 & 4: Frequency American Red Cross, Cohort of CY2008 whole blood donors followed for 365 days (6,466,231 donations)

  10. Questions 3 & 4: Frequency *Based on fractional estimates for frequency: 4.33 for men; 3.25 for women American Red Cross, Cohort of CY2008 whole blood donors followed for 365 days (6,466,231 donations)

  11. Balance Sheet

  12. Conclusions • In the ARC system, changing the minimum hemoglobin requirement to13.0 g/dL for men and 12.0 g/dL for women is predicted to have little effect on total collections • Changing the donation interval is predicted to have a significant, detrimental effect on collections

  13. Donation Frequency – Cohort • Day 1              Donation 1 • Day 57            Donation 2 • Day 113 Donation 3 • Day 169          Donation 4 • Day 225          Donation 5 • Day 281          Donation 6 • Day 337          Donation 7 • And 28 days left until New Years.

  14. Model Donation Interval Original Interval 0 56 d 56 d 56 d 56 d 56 d = 6 donations New Interval 0 112 d 112 d = 3 donations

  15. Donation Interval – Male Donors

  16. Donation Interval – Female Donors

More Related