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Drugs/chemicals used in aquaculture

Drugs/chemicals used in aquaculture. Feed additives (Sulfonamides) Sulfamerazine (fish grade) and Romet-30 Effective for bacterial infections Toxicity may occur - Kidney damage (drug crystal formation in renal tubules) Clinical signs – bloating/dropsy (stomach full of water)

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Drugs/chemicals used in aquaculture

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  1. Drugs/chemicals used in aquaculture Feed additives (Sulfonamides) • Sulfamerazine (fish grade) and Romet-30 • Effective for bacterial infections • Toxicity may occur - • Kidney damage (drug crystal formation in renal tubules) • Clinical signs – bloating/dropsy (stomach full of water) • Commercial availability in feed has limited many problems

  2. Drugs/chemicals used in aquaculture Sulfonamides (continued) • Sulfamerazine (fish grade) • No longer available • Romet-30 • Suggested dose (furunculosis) – 50mg/kg fish/day for 5 to 7 days • Also effective for ESC

  3. Drugs/chemicals used in aquaculture Terramycin (oxytetracycline) – TM50 • Generally drug of choice in aquaculture • Recommended dose – 55-83mg/Kg fish/day for 10 days • Effective against gram neg. bacteria (BKD?) • ERM, Furunculosis, CWD, etc. • Should not be fed on prophylactic basis! • Resistance to oxytetracycline can occur in most bacterial fish pathogens (Meyer and Schnick 1989)

  4. Drugs/chemicals used in aquaculture Therapeutants added to water • Methods • Static bath – most reliable for raceways/tanks/troughs • Constant flow – safe and can be used in most situations when fish reared in running water • Prolonged – • Chemicals • Formalin • Most widely used agent in fish culture • (solution contains 37% formaldehyde in water)

  5. Drugs/chemicals used in aquaculture • Chemicals (cont.) • Quaternary Ammonium compounds • Benzalkonium chloride/Hyamine • Now only limited use in food fish • Potassium Permanganate • Strong oxidizing agent

  6. Drugs/chemicals used in aquaculture • Chemicals (cont.) • Copper Sulfate • Algaecide/bactericide/parasiticide • Can produce kidney necrosis, destruction of hematopoietic tissue, increased liver fat and inhibition of digestive enzymes. • NaCl (salt) • Most overlooked treatment • Can be very effective • 3% recommended if possible (10-30 min)

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