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How Do You Select Patients for EGFR-targeted Therapy?

How Do You Select Patients for EGFR-targeted Therapy?. Disclosure (Lee M. Ellis). EGF Receptor: Its Role in CRC Therapy. Selecting Patients for Anti-EGFR-Targeted Therapies in CRC. Selection of Patients for EGFR-Targeted Therapies B ased on EGFR- Positivity.

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How Do You Select Patients for EGFR-targeted Therapy?

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  1. How Do You Select Patients for EGFR-targeted Therapy?

  2. Disclosure (Lee M. Ellis)

  3. EGF Receptor: Its Role in CRC Therapy

  4. Selecting Patients for Anti-EGFR-Targeted Therapies in CRC

  5. Selection of Patients for EGFR-TargetedTherapies Based on EGFR-Positivity

  6. Selecting Patients for Anti-EGFR-Targeted Therapies in CRC

  7. Bypass Pathways and EGFR Resistance

  8. KRAS Mutation as a Predictive Biomarker for EGFR MoAB Activity

  9. Single Agent Anti-EGFR Therapy /RAS Mutation Studies

  10. Wild-type KRAS is Required for PanitumumabEfficacy in Patients with Metastatic CRC

  11. Third-line PanitumumabvsBest Supportive Care: Impact of KRASMutations on PFS

  12. Effect of RAS Mutational Status on Growth Kinetics of Patients Treated with Cetuximab

  13. Chemotherapy Plus Anti-EGFR Therapy / RAS Mutation Studies

  14. KRAS Mutations as a Predictive Factor in Patients Treated with Cetuximab

  15. First-line Cetuximab in mCRC: Impact of KRAS Mutations in Patients Receiving Cetuximab (q2w) ± FOLFIRI

  16. Data from ASCO 2008

  17. FOLFOX4 ± Cetuximab as First-line Therapy of mCRC (OPUS): Effect of RAS Mutational Status

  18. Relationship of Efficacy and KRAS Status in Patients With Irinotecan- Refractory mCRC Treated With irinotecan and Escalating Doses of Cetuximab: The EVEREST Experience (Preliminary Data)

  19. Bypass Pathways and EGFR Resistance

  20. Loss of Expression of PTEN Predicts CetuximabEfficacy in Metastatic CRC

  21. Selecting Patients for Anti-EGFR-Targeted Therapies in CRC

  22. EGFR LigandsAmphiregulin / Epiregulin

  23. Epiregulin and Amphiregulin: Association with Response to CetuximabMonotherapy

  24. Epiregulin / Amphiregulin in KRAS Wild-type Patients Receiving Cetuximab + Irinotecan

  25. Biomarkers for EGFR-Targeted Therapies for mCRC

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