chuong
Uploaded by
15 SLIDES
326 VUES
150LIKES

Understanding WHO Stages of HIV Infection: Insights from Dr. Alap Mehta, Senior Medical Officer

DESCRIPTION

Dr. Alap Mehta, Senior Medical Officer at the ART Centre, New Civil Hospital, Surat, outlines the WHO staging of HIV infection based on clinical presentation and CD4+ counts. The stages include acute retroviral syndrome, asymptomatic chronic HIV, symptomatic HIV infection, and AIDS. Each stage has specific clinical manifestations, associated conditions, and recommended interventions. Early diagnosis and timely management are crucial for improving health outcomes. This comprehensive overview emphasizes the importance of monitoring CD4+ levels and recognizing opportunistic infections.

1 / 15

Télécharger la présentation

Understanding WHO Stages of HIV Infection: Insights from Dr. Alap Mehta, Senior Medical Officer

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. WHO STAGING (CLINICAL & CD4+ )DR.ALAP MEHTA(SENIOR MEDICAL OFFICER)ART CENTRE ,NEW CIVIL HOSPITAL,SURAT.

  2. CD4 count and OIs

  3. STAGES OF HIV INFECTION Viral transmission 2-3 wks. Acute Retroviral syndrome 2-3 wks. Recovery + Sero-conversion 2-4 wks. Asymptomatic chronic HIV infection Avg. 8 yrs Symptomatic HIV infection / AIDS Avg. 1.3 yrs

  4. WHO STAGE-1 • Asymptomatic OR Generalized Lymphadenopathy OR Acute Retroviral syndrome • Duration is almost 3-5 Years after infection • The symptoms of acute HIV infection usually develop within days to weeks after exposure and usually last less than 14 days. • A quantitative plasma HIV-1 RNA viral load of greater than 50,000 copies per mL in the absence of HIV antibodies establishes the diagnosis of acute HIV syndrome.

  5. Acute Retroviral Syndrome • Fever > 80 to 90% • Fatigue > 70 to 90% • Rash > 40 to 80% • diarrhea > 30 to 60% • Lymphadenopathy > 40 to 70% • Pharyngitis > 50 to 70% • Myalgia or arthralgia > 50 to 70% • STDS > 20 to 25%

  6. WHO STAGE II • Duration is 2-3 Years • Most common presentations are URTI, Oral Ulcers, Skin manifestations, Weight loss ( <10% of Body Weight) • Usually CD4+ count of the patient is > 350

  7.  CLINICAL FINDINGS • Unexplained moderate weight loss (<10% of presumed or measured body weight) • Recurrent respiratory tract infections (sinusitis, tonsillitis, otitis media, pharyngitis) • Herpes zoster • Angular cheilitis • Recurrent oral ulceration • Papular pruritic eruptions • Seborrhoeic dermatitis • Fungal nail infections

  8. WHO STAGE III • Most common stage of presentation of the patient to clinician • Usually CD4+ of the patient is between 100 to 350 • Most common presenting complains are 1. Chronic Diarrhea ( > 1 Month & do not responding to conventional Anti - Diarrheal therapy ) , 2. Chronic Fever ( > 1 Month ) , 3. Weight Loss ( > 10 % of the Body weight )

  9. CLINICAL CONDITIONS • Unexplained severe weight loss (>10% of presumed or measured body weight) • Unexplained chronic diarrhoea for longer than one month • Unexplained persistent fever (above 37.5oC intermittent or constant for longer than one month) • Persistent oral candidiasis • Oral hairy leukoplakia • Pulmonary tuberculosis • Severe bacterial infections (e.g. pneumonia, empyema, pyomyositis, bone or joint infection, meningitis, • bacteraemia) • Acute necrotizing ulcerative stomatitis, gingivitis or periodontitis

  10. WHO STAGE IV • Terminal Stage of the Disease • CD 4+ < 100 • Multi Organ involvement • CNS Manifestations are occurs in this stage

  11. CLINICAL FINDINGS GENERALISED CONDITIONS • HIV wasting syndrome GASTROINTESTINAL • Oesophageal candidiasis • Chronic cryptosporidiosis • Chronic isosporiasis • Abdominal Koch’s RESIRATORY TRACT • Pneumocystis pneumonia • Recurrent severe bacterial pneumonia • Candidiasis of trachea, bronchi or lungs • Histoplasmosis ( Continue)

  12. CENTRAL NERVOUS SYSTEM • Central nervous system toxoplasmosis • HIV encephalopathy • Cryptococcosis meningitis • Progressive multifocal leukoencephalopathy • TB meningitis OTHERS • Symptomatic HIV-associated nephropathy • Symptomatic HIV-associated cardiomyopathy • Lymphoma (cerebral or B cell non-Hodgkin) • Invasive cervical carcinoma • Kaposi sarcoma

  13. SPECIAL COSIDERATION Following diseases can present irrespective of CD4+ cell count level • Tuberculosis • Candidiasis • Herpes Zoster • STDs

  14.  WHEN TO START ART

  15. STOP AIDS. KEEP THE PROMISE.  THANK YOU

More Related